Transaction in Own Shares

AstraZeneca PLC
17 December 2007



REPURCHASE OF SHARES IN ASTRAZENECA PLC


AstraZeneca PLC announced that on 14 December 2007, it purchased for
cancellation 800,000 ordinary shares of AstraZeneca PLC at a price of 2271 pence
per share. Upon the cancellation of these shares, the number of shares in issue
will be 1,456,866,319.





G H R Musker

Company Secretary

17 December 2007


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