Transaction in Own Shares

AstraZeneca PLC
21 November 2007

REPURCHASE OF SHARES IN ASTRAZENECA PLC





AstraZeneca PLC announced that on 20 November 2007, it purchased for
cancellation 800,000 ordinary shares of AstraZeneca PLC at a price of 2126 pence
per share. Upon the cancellation of these shares, the number of shares in issue
will be 1,460,905,654.





G H R Musker

Company Secretary

21 November 2007


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