Transaction in Own Shares

AstraZeneca PLC
22 November 2004

                       REPURCHASE OF SHARES IN ASTRAZENECA PLC

AstraZeneca PLC announced that on 19 November 2004, it purchased for
cancellation 2,500,000 ordinary shares of AstraZeneca PLC at a price of 2180
pence per share. Upon the cancellation of these shares, the number of shares in
issue will be 1,654,046,096.

G H R Musker
Company Secretary
22 November 2004


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