Transaction in Own Shares

AstraZeneca PLC
25 February 2005


                  REPURCHASE OF SHARES IN ASTRAZENECA PLC


AstraZeneca PLC announced that on 24 February 2005, it purchased for
cancellation 750,000 ordinary shares of AstraZeneca PLC at a price of 2118 pence
per share. Upon the cancellation of these shares, the number of shares in issue
will be 1,638,612,261.



G H R Musker
Company Secretary
25 February 2005





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