Transaction in Own Shares

AstraZeneca PLC
16 February 2007



                     REPURCHASE OF SHARES IN ASTRAZENECA PLC

Further to the announcement of its irrevocable, non-discretionary share
repurchase programme for the period 5 February 2007 to 30 April 2007,
AstraZeneca PLC announced that under the terms of that programme it purchased
for cancellation 288,228 ordinary shares of AstraZeneca PLC at a price of 2940
pence per share on 15 February 2007. Upon the cancellation of these shares, the
number of shares in issue will be 1,529,431,334.



G H R Musker
Company Secretary

16 February 2007


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