Transaction in Own Shares

AstraZeneca PLC
27 May 2005



                  REPURCHASE OF SHARES IN ASTRAZENECA PLC

AstraZeneca PLC announced that on 26 May 2005, it purchased for cancellation
300,000 ordinary shares of AstraZeneca PLC at a price of 2336 pence per share.
Upon the cancellation of these shares, the number of shares in issue will be
1,627,684,662.







G H R Musker

Company Secretary

27 May 2005


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