Transaction in Own Shares

AstraZeneca PLC
31 October 2005




REPURCHASE OF SHARES IN ASTRAZENECA PLC


AstraZeneca PLC announced that on 28 October 2005, it purchased for cancellation
2,000,000 ordinary shares of AstraZeneca PLC at a price of 2478 pence per share.
Upon the cancellation of these shares, the number of shares in issue will be
1,595,440,917.







G H R Musker

Company Secretary

31 October 2005


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