Transaction in Own Shares

AstraZeneca PLC
04 September 2007

REPURCHASE OF SHARES IN ASTRAZENECA PLC

Further to the announcement of its irrevocable, non-discretionary share
repurchase programme for the period 2 July 2007 to 31 October 2007, AstraZeneca
PLC announced that under the terms of that programme it purchased for
cancellation 235,839 ordinary shares of AstraZeneca PLC at a price of 2432 pence
per share on 3 September 2007. Upon the cancellation of these shares, the number
of shares in issue will be 1,481,255,399.

G H R Musker
Company Secretary
4 September 2007


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