Transaction in Own Shares

AstraZeneca PLC
21 June 2005



                    REPURCHASE OF SHARES IN ASTRAZENECA PLC

AstraZeneca PLC announced that on 20 June 2005, it purchased for cancellation
800,000 ordinary shares of AstraZeneca PLC at a price of 2280 pence per share.
Upon the cancellation of these shares, the number of shares in issue will be
1,619,453,036.





G H R Musker

Company Secretary

21 June 2005


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