Transaction in Own Shares

AstraZeneca PLC
04 November 2005


                  REPURCHASE OF SHARES IN ASTRAZENECA PLC 


AstraZeneca PLC announced that on 3 November 2005, it purchased for cancellation
500,000 ordinary shares of AstraZeneca PLC at a price of 2560 pence per share.
Upon the cancellation of these shares, the number of shares in issue will be
1,594,190,917.







G H R Musker
Company Secretary
4 November 2005


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