Transaction in Own Shares

AstraZeneca PLC
11 September 2007


                    REPURCHASE OF SHARES IN ASTRAZENECA PLC

Further to the announcement of its irrevocable, non-discretionary share
repurchase programme for the period 2 July 2007 to 31 October 2007, AstraZeneca
PLC announced that under the terms of that programme it purchased for
cancellation 242,436 ordinary shares of AstraZeneca PLC at a price of 2359 pence
per share on 10 September 2007. Upon the cancellation of these shares, the
number of shares in issue will be 1,479,569,297.


G H R Musker
Company Secretary
11 September 2007


                      This information is provided by RNS
            The company news service from the London Stock Exchange