Transaction in Own Shares

AstraZeneca PLC
04 December 2006

                    REPURCHASE OF SHARES IN ASTRAZENECA PLC

AstraZeneca PLC announced that on 1 December 2006, it purchased for cancellation
800,000 ordinary shares of AstraZeneca PLC at a price of 2895 pence per share.
Upon the cancellation of these shares, the number of shares in issue will be
1,533,903,123.







G H R Musker
Company Secretary
4 December 2006


                      This information is provided by RNS
            The company news service from the London Stock Exchange