Transaction in Own Shares

AstraZeneca PLC
14 September 2007



                      REPURCHASE OF SHARES IN ASTRAZENECA PLC

Further to the announcement of its irrevocable, non-discretionary share
repurchase programme for the period 2 July 2007 to 31 October 2007, AstraZeneca
PLC announced that under the terms of that programme it purchased for
cancellation 240,579 ordinary shares of AstraZeneca PLC at a price of 2381 pence
per share on 13 September 2007. Upon the cancellation of these shares, the
number of shares in issue will be 1,478,852,291.



G H R Musker
Company Secretary
14 September 2007


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