Transaction in Own Shares

AstraZeneca PLC
20 September 2007

This announcement replaces that issued under RNS No. 1417E.

The 'shares in issue' number has been corrected.





REPURCHASE OF SHARES IN ASTRAZENECA PLC


Further to the announcement of its irrevocable, non-discretionary share
repurchase programme for the period 2 July 2007 to 31 October 2007, AstraZeneca
PLC announced that under the terms of that programme it purchased for
cancellation 238,836 ordinary shares of AstraZeneca PLC at a price of 2401 pence
per share on 19 September 2007. Upon the cancellation of these shares, the
number of shares in issue will be 1,476,640,338.




G H R Musker
Company Secretary
20 September 2007


                      This information is provided by RNS
            The company news service from the London Stock Exchange