Transaction in Own Shares

AstraZeneca PLC
10 August 2005



                    REPURCHASE OF SHARES IN ASTRAZENECA PLC


AstraZeneca PLC announced that on 9 August 2005, it purchased for cancellation
1,000,000 ordinary shares of AstraZeneca PLC at a price of 2588 pence per share.
Upon the cancellation of these shares, the number of shares in issue will be
1,614,835,166.


G H R Musker
Company Secretary
10 August 2005





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