Transaction in Own Shares

AstraZeneca PLC
10 August 2006



                    REPURCHASE OF SHARES IN ASTRAZENECA PLC


AstraZeneca PLC announced that on 9 August 2006, it purchased for cancellation
1,250,000 ordinary shares of AstraZeneca PLC at a price of 3178 pence per share.
Upon the cancellation of these shares, the number of shares in issue will be
1,562,554,658.







G H R Musker

Company Secretary

10 August 2006


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