Transaction in Own Shares

AstraZeneca PLC
31 March 2006

REPURCHASE OF SHARES IN ASTRAZENECA PLC

AstraZeneca PLC announced that on 30 March 2006, it purchased for cancellation
300,000 ordinary shares of AstraZeneca PLC at a price of 2914 pence per share.
Upon the cancellation of these shares, the number of shares in issue will be
1,578,466,401.

G H R Musker
Company Secretary
31 March 2006


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