Transaction in Own Shares

AstraZeneca PLC
27 March 2007


                       REPURCHASE OF SHARES IN ASTRAZENECA PLC



AstraZeneca PLC announced that on 26 March 2007, it purchased for cancellation
1,404,593 ordinary shares of AstraZeneca PLC at a price of 2779 pence per share.

Some of these shares were purchased under the terms of the previously announced
irrevocable, non-discretionary share repurchase programme for the period 5
February 2007 to 30 April 2007.

Upon the cancellation of these shares, the number of shares in issue will be
1,513,878,973.


G H R Musker
Company Secretary
27 March 2007


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