Transaction in Own Shares

AstraZeneca PLC
25 June 2007


REPURCHASE OF SHARES IN ASTRAZENECA PLC


AstraZeneca PLC announced that on 22 June 2007, it purchased for cancellation
750,000 ordinary shares of AstraZeneca PLC at a price of 2563 pence per share.
Upon the cancellation of these shares, the number of shares in issue will be
1,495,319,481.


G H R Musker
Company Secretary
25 June 2007


                      This information is provided by RNS
            The company news service from the London Stock Exchange               MMTBLR