Transaction in Own Shares

AstraZeneca PLC
03 April 2006

REPURCHASE OF SHARES IN ASTRAZENECA PLC



AstraZeneca PLC announced that on 31 March 2006, it purchased for cancellation
750,000 ordinary shares of AstraZeneca PLC at a price of 2904 pence per share.
Upon the cancellation of these shares, the number of shares in issue will be
1,578,166,352.



G H R Musker

Company Secretary

3 April 2006


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