Zestril Market Exclusivity

AstraZeneca PLC 26 November 2001 AstraZeneca Receives Six Months' Market Exclusivity for ZESTRIL(R) (lisinopril) AstraZeneca announced today that the U.S. Food and Drug Administration (FDA) granted six months' market exclusivity for the ACE inhibitor ZESTRIL(R) (lisinopril) after the company complied with the FDA's written request for information on the use of the medication in children. The additional six months' exclusivity extends AstraZeneca's US market protection for currently marketed drug products containing lisinopril, which include ZESTRIL(R) and ZESTORETIC(R) (lisinopril and hydrochlorthiazide) Tablets, through June 29, 2002. Date: 26 November 2001 Media Enquiries: Emily Denney, Tel: +44 (0) 207 304 5034 Steve Brown, Tel: +44 (0) 207 304 5033 Investor Relations: Jorgen Winroth, Tel: +1 609 896 4148 Mina Blair Robinson, Tel: +44 (0) 207 304 5084 -Ends-

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