13 November 2017
Avacta Group plc
("Avacta", "the Group" or "the Company")
Avacta's Chief Scientific Officer to Present Therapeutics Update at PEGS Europe
Avacta Group plc (AIM: AVCT), the developer of Affimer® biotherapeutics and reagents, is pleased to announce that its Chief Scientific Officer, Dr Amrik Basran, will be presenting an update on the Affimer therapeutics programmes at the Protein and Antibody Engineering Summit, 13-17 November 2017 in Lisbon, Portugal.
Dr Basran will present recent progress in the Affimer therapeutic programmes and will focus on PD-L1 immune checkpoint inhibitors and half life extension methods.
Dr Basran will discuss new data concerning a range of Affimer proteins that bind to serum albumin, which can be used to form bispecifics to extend serum half-life. A range of species specific (human, mouse, cynomolgus monkey and dog) albumin binders have been generated and data will be presented that show that these molecules significantly extend the serum half-life of the Affimer scaffold and therefore offer a valuable alternative to other methods for the creation of biotherapeutics with long serum half-life.
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About Avacta Group plc (www.avacta.com)
Avacta's principal focus is on its proprietary Affimer® technology which is a novel engineered alternative to antibodies that has wide application in Life Sciences for diagnostics, therapeutics and general research and development.
Antibodies dominate markets worth in excess of $100bn despite their shortcomings. Affimer technology has been designed to address many of these negative performance issues, principally; the time taken to generate new antibodies, the reliance on an animal's immune response, poor specificity in many cases, and batch to batch variability. Affimer technology is based on a small protein that can be quickly generated to bind with high specificity and affinity to a wide range of protein targets.
Avacta has a pre-clinical biotech development programme with an in-house focus on immuno-oncology and bleeding disorders as well as partnered development programmes. Avacta is commercialising non-therapeutic Affimer reagents through licensing to developers of life sciences research tools and diagnostics.
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