Major Interests in Shares

Banco Santander Central Hispano SA
14 September 2007


NOTIFICATION OF MAJOR INTERESTS IN SHARES

1. Name of company

BANCO SANTANDER, S. A.....................................

2. Name of shareholder having a major interest

STATE STREET BANK AND TRUST CO........................................

3. Please state whether notification indicates that it is in respect of holding
of the shareholder named in 2 above or 
in respect of a non-beneficial interest or in the case of an individual holder 
if it is a holding of that person's 
spouse or children under the age of 18

AS IN 2 ABOVE.........................................................

4. Name of the registered holder(s) and, if more than one holder, the number of
shares held by each of them

AS IN 2 ABOVE.........................................................

5. Number of shares / amount of stock acquired

10,023,483............................................................

6. Percentage of issued class

0.160%............................................................

7. Number of shares / amount of stock disposed

...............................................................................

8. Percentage of issued class

............................................................

9. Class of security

ORDINARY SHARES OF 0.50 EURO NOMINAL VALUE EACH .....................

10. Date of transaction

ON 6 SEPTEMBER 2007......................................................

11. Date company informed

ON 14 SEPTEMBER 2007......................................................

12. Total holding following this notification

316,584,914 SHARES...................................................

13. Total percentage holding of issued class following this notification

5.075%............................................................

14. Any additional information

TO OUR KNOWLEDGE NO PERSON BENEFICIALLY OWNS, DIRECTLY OR INDIRECTLY, 5% OR 
MORE OF OUR SHARES.............................................

15. Name of contact and telephone number for queries

PEDRO DE MINGO; + (34) 91 289 3390...................................

16. Name and signature of authorised company official responsible for making 
this notification

JOSE MANUEL DE ARALUCE................................................

Date of notification

ON 14 SEPTEMBER 2007.................................................

The FSA does not give any express or implied warranty as to the accuracy of 
this document or material and does not 
accept any liability for error or omission. The FSA is not liable for any 
damages (including, without limitation, 
damages for loss of business or loss of profits) arising in contract, tort 
or otherwise from the use of or inability to 
use this document, or any material contained in it, or from any action or 
decision taken as a result of using this 
document or any such material.



                      This information is provided by RNS
            The company news service from the London Stock Exchange