Major Intersts in Shares

Banco Santander S.A.
24 January 2008


NOTIFICATION OF MAJOR INTERESTS IN SHARES

1. Name of company

BANCO SANTANDER, S. A.....................................

2. Name of shareholder having a major interest

JP Morgan Chase & Co. and subsidiaries........................................

3. Please state whether notification indicates that it is in respect of 
holding of the shareholder named in 2 above or in respect of a non-beneficial 
interest or in the case of an individual holder if it is a holding of that 
person's spouse or children under the age of 18

AS IN 2 ABOVE.........................................................

4. Name of the registered holder(s) and, if more than one holder, the number 
of shares held by each of them

AS IN 2 ABOVE.........................................................

5. Number of shares / amount of stock acquired

............................................................

6. Percentage of issued class

............................................................

7. Number of shares / amount of stock disposed

14,277,238....................................................................

8. Percentage of issued class

0.228%............................................................

9. Class of security

ORDINARY SHARES OF 0.50 EURO NOMINAL VALUE EACH .....................

10. Date of transaction

ON 17 JANUARY 2008......................................................

11. Date company informed

ON 23 JANUARY 2008......................................................

12. Total holding following this notification

174,171,278 SHARES...................................................

13. Total percentage holding of issued class following this notification

2.787% TAKING INTO ACCOUNT TREASURY SHARES WHEN CALCULATING PERCENTAGE. 
2.785% NOT TAKING INTO ACCOUNT TREASURY SHARES..........................

14. Any additional information



15. Name of contact and telephone number for queries

PEDRO DE MINGO; + (34) 91 289 3390...................................

16. Name and signature of authorised company official responsible for 
making this notification

JOSE MANUEL DE ARALUCE................................................

Date of notification

ON 24 JANUARY 2008.................................................

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