Rule 8.3 - ALLIANCE UNICHEM PLC

FORM 8.3 DEALINGS BY PERSONS WHO OWN OR CONTROL 1% OR MORE OF ANY CLASS OF RELEVANT SECURITY (Rule 8.3 of The City Code on Takeovers and Mergers) Name of purchaser/vendor * BARCLAYS PLC Company dealt in ALLIANCE UNICHEM PLC Relevant security dealt in ORD GBP 0. 10 If a connected EFM, name of offeree/offeror with which connected If a connected EFM, nature of connection # Date of dealing 12 OCTOBER 2005 DEALINGS † Amount bought Price per unit (currency must be stated) 252 7.9150 600,000 7.9511 Amount sold Price per unit (currency must be stated) Resultant total amount and percentage of the same relevant security owned or controlled 29,691,278 (8.21%) IS A SUPPLEMENTAL FORM 8 (DERIVATIVE)/FORM 8 (OPTION) ATTACHED? YES Date of disclosure 13 OCTOBER 2005 Contact name BARCLAYS CORPORATE SECRETARIAT Telephone number 0207 116 2913 * Specify the owner or controller in addition to the person dealing. The naming of nominees or vehicle companies is insufficient. In the case of disclosure of dealings by fund managers on behalf of discretionary clients, the clients need not be named. # See the definition of "connected fund managers and principal traders" in the Definitions Section of the Code. † If disclosing dealings/holdings in derivatives or options, please attach Supplemental Form 8 (Derivative) or Supplemental Form 8 (Option), as appropriate. For details of the Code's dealing disclosure requirements, see Rule 8 and its Notes which can be viewed on the Takeover Panel's website at www.thetakeoverpanel.org.uk. SUPPLEMENTAL FORM 8 (DERIVATIVE) DEALINGS/HOLDINGS IN DERIVATIVES (This form should be attached to Form 8.1, Form 8.1(b)(ii), Form 8.2 or Form 8.3, as appropriate) Description of all derivative products CFD - A purchaser of a CFD will realise disclosed on this form a gain if the price of the underlying security goes up. A seller of a CFD will realise a gain if the price of the underlying security goes down. The CFD contracts are open ended and there is no rollover into new contracts. Full details of any agreement, arrangement None or understanding between the person disclosing and any other person relating to the voting rights or future acquisition or disposal of any relevant securities to which any derivative referred to on this form is referenced. If none, this should be stated. WRITING/ENTERING INTO A DERIVATIVE Product name Transaction Writing/ Number of Reference price Maturity date eg long CFD date entering into securities (currency (indicate as to which the must be stated) applicable) derivative is referenced CLOSING OUT A DERIVATIVE Product name Transaction Number of Reference price Closing out price eg long CFD date securities (currency (currency must be to which the must be stated) stated) derivative is referenced DETAILS OF OPEN DERIVATIVES (excluding any transaction set out above) Product name Transaction Written/ Number of Reference price Maturity date eg long CFD date entered into securities (currency (indicate as to which the must be stated) applicable) derivative is referenced Long CFD 22/11/2001 Entered into 18,916 5.3600 Short CFD 01/03/2002 Entered into 77,337 5.4850 Long CFD 07/03/2002 Entered into 33,784 5.6000 Short CFD 14/08/2002 Entered into 13,620 5.8000 Short CFD 16/08/2002 Entered into 47,020 6.0000 Short CFD 16/08/2002 Entered into 2,319 6.0000 Short CFD 20/08/2002 Entered into 2,977 5.8019 Short CFD 09/01/2003 Entered into 26,261 4.6750 Short CFD 10/01/2003 Entered into 27,056 4.7485 Short CFD 17/01/2003 Entered into 34,497 4.5105 Short CFD 06/02/2003 Entered into 29,565 4.1263 Short CFD 24/03/2003 Entered into 177,686 4.3476 Long CFD 27/05/2003 Entered into 25,469 4.9925 Long CFD 28/05/2003 Entered into 25,458 4.9836 Long CFD 29/05/2003 Entered into 25,100 4.9665 Long CFD 29/05/2003 Entered into 10,040 4.9850 Long CFD 11/06/2003 Entered into 27,921 5.0309 Long CFD 13/06/2003 Entered into 36,796 5.0137 Long CFD 16/06/2003 Entered into 32,008 5.0023 Long CFD 17/06/2003 Entered into 53,620 5.0037 Long CFD 17/06/2003 Entered into 16,356 5.0122 Long CFD 19/06/2003 Entered into 38,778 5.0119 Long CFD 23/06/2003 Entered into 32,541 5.0500 Long CFD 24/06/2003 Entered into 92,565 4.8959 Long CFD 25/06/2003 Entered into 81,927 4.8858 Long CFD 26/06/2003 Entered into 68,783 4.9068 Long CFD 08/07/2003 Entered into 10,384 4.8849 Long CFD 08/07/2003 Entered into 51,263 4.8849 Long CFD 25/07/2003 Entered into 43,204 4.9582 Long CFD 05/08/2003 Entered into 60,190 4.8350 Long CFD 05/08/2003 Entered into 6,009 4.8350 Long CFD 06/08/2003 Entered into 65,107 4.7900 Long CFD 07/08/2003 Entered into 26,042 4.8290 Long CFD 08/08/2003 Entered into 33,996 4.8150 Long CFD 11/08/2003 Entered into 50,980 4.8550 Long CFD 12/08/2003 Entered into 23,243 4.9465 Long CFD 12/08/2003 Entered into 8,879 4.9465 Long CFD 14/08/2003 Entered into 2,721 4.9386 Long CFD 14/08/2003 Entered into 25,422 4.9386 Long CFD 15/08/2003 Entered into 10,173 4.9600 Long CFD 15/08/2003 Entered into 33,607 4.9728 Long CFD 19/08/2003 Entered into 108,595 4.9675 Long CFD 21/08/2003 Entered into 25,922 5.0280 Long CFD 21/08/2003 Entered into 10,044 5.0280 Long CFD 22/08/2003 Entered into 31,282 5.0720 Long CFD 26/08/2003 Entered into 30,662 5.0788 Long CFD 10/09/2003 Entered into 22,798 5.4227 Short CFD 29/09/2003 Entered into 89,664 5.2200 Long CFD 29/09/2003 Entered into 89,664 5.2200 Short CFD 08/10/2003 Entered into 112,885 5.3272 Short CFD 10/10/2003 Entered into 23,020 5.4414 Short CFD 21/10/2003 Entered into 22,769 5.4427 Short CFD 06/01/2004 Entered into 88,606 5.1345 Short CFD 16/01/2004 Written 1,100 5.0506 Long CFD 19/01/2004 Written 1,100 5.1444 Short CFD 22/01/2004 Written 12,500 5.0935 Long CFD 23/01/2004 Written 12,500 5.0240 Short CFD 27/01/2004 Written 2,400 4.9527 Short CFD 28/01/2004 Written 23,500 4.9730 Long CFD 29/01/2004 Written 4,900 4.9108 Short CFD 02/02/2004 Written 17,800 4.9161 Short CFD 03/02/2004 Written 3,100 4.8756 Short CFD 06/02/2004 Written 5,600 4.9343 Short CFD 09/02/2004 Written 19,100 4.9112 Short CFD 10/02/2004 Written 800 4.9006 Long CFD 11/02/2004 Written 900 4.9944 Short CFD 13/02/2004 Written 2,300 4.9856 Short CFD 16/02/2004 Written 1,200 4.9906 Short CFD 18/02/2004 Written 700 4.9856 Long CFD 23/02/2004 Written 31,700 5.3453 Long CFD 24/02/2004 Written 7,100 5.3545 Long CFD 25/02/2004 Written 20,000 5.4066 Long CFD 04/03/2004 Written 6,500 5.4675 Long CFD 09/03/2004 Written 5,400 5.5182 Long CFD 12/03/2004 Written 900 5.5293 Long CFD 15/03/2004 Written 14,100 5.5971 Long CFD 16/03/2004 Written 17,200 5.5772 Short CFD 19/03/2004 Written 1,200 5.6307 Long CFD 25/03/2004 Written 3,800 5.7252 Long CFD 26/03/2004 Written 2,100 5.6743 Long CFD 30/03/2004 Written 1,600 5.7543 Long CFD 31/03/2004 Written 15,600 5.7846 Long CFD 01/04/2004 Written 14,000 5.7897 Long CFD 01/04/2004 Written 900 5.7793 Long CFD 05/04/2004 Written 5,000 5.9032 Long CFD 05/04/2004 Written 8,400 5.9745 Short CFD 07/04/2004 Written 1,000 5.8257 Long CFD 16/04/2004 Written 3,479 5.9311 Short CFD 16/04/2004 Written 20,800 5.9334 Short CFD 19/04/2004 Written 700 5.9707 Short CFD 20/04/2004 Written 22,500 6.1066 Long CFD 22/04/2004 Written 500 6.0143 Long CFD 26/04/2004 Written 7,300 6.0616 Short CFD 27/04/2004 Entered into 8,244 6.0382 Long CFD 28/04/2004 Written 10,400 5.9630 Short CFD 05/05/2004 Entered into 9,355 5.9700 Short CFD 05/05/2004 Entered into 2,090 5.9700 Long CFD 11/05/2004 Written 11,200 5.9080 Long CFD 12/05/2004 Written 11,000 5.9958 Short CFD 13/05/2004 Written 600 5.9857 Long CFD 20/05/2004 Written 900 5.9943 Short CFD 20/05/2004 Written 22,480 5.9800 Long CFD 24/05/2004 Written 1 5.9500 Short CFD 24/05/2004 Entered into 27,522 5.9350 Long CFD 25/05/2004 Written 3,000 5.9393 Long CFD 26/05/2004 Written 800 6.0493 Long CFD 28/05/2004 Written 1,200 6.1543 Short CFD 28/05/2004 Entered into 23,585 6.1696 Short CFD 28/05/2004 Entered into 8,137 6.1696 Long CFD 01/06/2004 Written 19,000 6.2078 Long CFD 02/06/2004 Written 1,700 6.2348 Short CFD 03/06/2004 Entered into 8,058 6.2257 Long CFD 04/06/2004 Written 4,800 6.2866 Long CFD 07/06/2004 Written 5,700 6.4592 Short CFD 07/06/2004 Entered into 9,780 6.3950 Long CFD 08/06/2004 Written 2,400 6.3758 Short CFD 09/06/2004 Entered into 14,532 6.3850 Short CFD 11/06/2004 Entered into 22,608 6.2966 Short CFD 11/06/2004 Entered into 10,535 6.2966 Short CFD 14/06/2004 Entered into 1,577 6.3262 Short CFD 17/06/2004 Written 1,800 6.3658 Short CFD 17/06/2004 Entered into 7,770 6.3950 Short CFD 18/06/2004 Written 7,000 6.3881 Long CFD 25/06/2004 Written 500 6.5312 Long CFD 30/06/2004 Written 5,200 6.6248 Long CFD 01/07/2004 Written 1,000 6.6442 Long CFD 02/07/2004 Written 1,200 6.6192 Long CFD 06/07/2004 Written 9,200 6.6138 Long CFD 07/07/2004 Written 700 6.5492 Long CFD 08/07/2004 Written 8,400 6.5261 Long CFD 09/07/2004 Written 19,900 6.7302 Long CFD 12/07/2004 Written 22,400 6.7032 Long CFD 13/07/2004 Written

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