Rule 8.3 - CAMBRIDGE ANTIBODY TECHNOLOGY GROUP PLC

FORM 8.3 DEALINGS BY PERSONS WITH INTERESTS IN SECURITIES REPRESENTING 1% OR MORE (Rule 8.3 of the City Code on Takeovers and Mergers) 1. KEY INFORMATION Name of person dealing BARCLAYS PLC (Note 1) Company dealt in CAMBRIDGE ANTIBODY TECHNOLOGY GROUP PLC Class of relevant security ORD GBP 0.10 to which the dealings being disclosed relate (Note 2) Date of dealing 15 June 2006 2. INTERESTS, SHORT POSITIONS AND RIGHTS TO SUBSCRIBE (a) Interests and short positions (following dealing) in the class of relevant security dealt in (Note 3) Long Short Number (%) Number (%) (1) Relevant 963,340 (1.81%) 275 (0.00%) securities (2) Derivatives 94 (0.00%) 53,488 (0.10%) (other than options) (3) Options and 0 (0.00%) 0 (0.00%) agreements to purchase/sell Total 963,434 (1.81%) 53,763 (0.10%) (b) Interests and short positions in relevant securities of the company, other than the class dealt in (Note 3) Class of Long Short relevant security: Number Number (%) (%) (1) Relevant securities (2) Derivatives (other than options) (3) Options and agreements to purchase/sell Total (c) Rights to subscribe (Note 3) Class of relevant security: Details 3. DEALINGS (Note 4) (a) Purchases and sales Purchase/sale Number of Securities Price per unit (GBP) Purchase 20,754 13.1200 (b) Derivatives transactions (other than options) Product Name Long/Short Number of Price per unit securities CFD Short 20754 13.12 (c) Options transactions in respect of existing securities (i) Writing, selling, purchasing or varying Product name, Writing, Number of Exercise Type, e.g. Expiry Option money e.g. call selling, securities to price American, date paid/received option purchasing, which the option European etc. per unit (Note 5) varying etc. relates (Note 7) (ii) Exercising Product name, e.g. Number of Exercise price per call option securities unit (Note 5) (d) Other dealings (including new securities) (Note 4) Nature of transaction Details Price per unit (Note 8) (if applicable) (Note 5) 4. OTHER INFORMATION Agreements, arrangements or understandings relating to options or derivatives Full details of any agreement, arrangement or understanding between the person disclosing and any other person relating to the voting rights of any relevant securities under any option referred to on this form or relating to the voting rights or future acquisition or disposal of any relevant securities to which any derivative referred to on this form is referenced. If none, this should be stated. Is a Supplemental Form 8 attached? (Note 9) NO Date of disclosure 16 June 2006 Contact name BARCLAYS COMPLIANCE Telephone number 0207 116 2913 If a connected EFM, name of offeree/offeror with which connected If a connected EFM, state nature of connection (Note 10) Notes The Notes on Form 8.3 can be viewed on the Takeover Panel's website at www.thetakeoverpanel.org.uk

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Barclays (BARC)
UK 100

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