Director Shareholding

Finsbury Life Sciences Inv Tst PLC
13 September 2000


1) NAME OF COMPANY                     2) NAME OF DIRECTOR
                                                      
  Finsbury Life Sciences Investment       Peter Keen
  Trust PLC              


3) Please state whether                4) Name of the registered holder(s)
   notification indicates that it is      and, if more than one holder, the
   in respect of holding of the           number of shares held by each of
   Director named in 2 above or           them. (if notified)
   holding of that person's spouse or                    
   children under the age of 18 or in                    
   respect of a non-beneficial            Not given
   interest                            

   The notification relates to the
   holding of Mr Keen's spouse,
   Mrs M J Keen,
                 

5) Please state whether                6) Please state the nature of the
   notification relates to a person(s)    transaction. For PEP transactions
   connected with the Director named      please indicate whether
   in 2 above and identify the            general/single co. PEP and if
   connected person(s)                    discretionary/non discretionary
                                                      
   The notification relates to the        Purchase of shares beneficially
   holding of Mr Keen's spouse,           owned by the Director's spouse.
   Mrs M J Keen,                          The shares were not purchased for a
                                          PEP or ISA.


7) Number of          8) (0.01 %)      9) Number of           10) (0.0 %)
   shares/amount of      of issued        shares/amount of        of issued
   stock acquired        Class            stock disposed          Class
                                              
   3,232                                  0


11) Class of          12) Price per    13) Date of         14) Date company
    security              share            transactions        informed
                                                              
    Ordinary Shares       210p             13 September        13 September 
    of 25p each                            2000                2000
                                    

15) Total holding following this        16) Total percentage holding of
    notification                            issued class following this
                                            notification
                                    
    13,232                                  0.04 %
                 

IF A DIRECTOR HAS BEEN GRANTED OPTIONS BY THE COMPANY PLEASE COMPLETE THE
FOLLOWING
BOXES

17) Date of grant                       18) Period during which or date on
                                            which exercisable
                                    
                                                      
19) Total amount paid (if any) for      20) Description of shares or
    grant of the option                     debentures involved:class, number
                                                      
                 
21) Exercise price (if fixed at         22) Total number of shares or
    time of grant) or indication that       debentures over which options held
    price is to be fixed at time of         following this notification
    exercise                                              
                                            0
                                                      

23) Any additional information          24) Name of contact and telephone
                                            number for queries
                                    
                                            Mr D Fallon  020 7426 6235
                                    
25) Name and signature of           
authorised company official            David Fallon
responsible for making this            for and on behalf of Close Finsbury
notification                           Asset Management Limited, Secretary


Date of Notification     
13 September 2000


The International Stock Exchange of the United Kingdom and the Republic of
Ireland Ltd.  Registered Office:The Stock Exchange, London, EC2N 1HP