Holding(s) in Company

Finsbury Life Sciences Inv Tst PLC
04 April 2003

                                  SCHEDULE 10

                   NOTIFICATION OF MAJOR INTERESTS IN SHARES

1. Name of company
Finsbury Life Sciences Investment Trust PLC

2. Name of shareholder having a major interest
Exeter Asset Management Limited

3. Please state whether notification indicates that it is in respect of holding
of the shareholder named in 2 above or in respect of a non-beneficial interest
or in the case of an individual holder if it is a holding of that person's
spouse or children under the age of 18
Notification in respect of portfolios under the management of Exeter Asset Management Limited

4. Name of the registered holder(s) and, if more than one holder, the number of
shares held by each of them
Not stated

5. Number of shares / amount of stock acquired
100,000

6. Percentage of issued class
0.33%

7. Number of shares / amount of stock disposed
N/A

8. Percentage of issued class
N/A

9. Class of security
Ordinary shares of 25p each

10. Date of transaction
2 April 2003





11. Date company informed
3 April 2003

12. Total holding following this notification
Exeter Managed Growth Fund - 500,000

Exeter Global Opportunities Fund - 650,000

Exeter Capital Growth Fund - 750,000

1,900,000



13. Total percentage holding of issued class following this notification
6.31%

14. Any additional information




15. Name of contact and telephone number for queries
Kelly Chandler - 020 7426 6219

16. Name and signature of authorised company official responsible for making
this notification
Alastair Smith, for and on behalf of Close Finsbury Asset Management

Date of notification
4 April 2003

The FSA does not give any express or implied warranty as to the accuracy of this
document or material and does not accept any liability for error or omission.
The FSA is not liable for any damages (including, without limitation, damages
for loss of business or loss of profits) arising in contract, tort or otherwise
from the use of or inability to use this document, or any material contained in
it, or from any action or decision taken as a result of using this document or
any such material.


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