Director Shareholding

Cambridge Antibody Tech Group PLC
3 December 2001


                                 SCHEDULE 11

         NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS

1) Name of company
Cambridge Antibody Technology


2) Name of director
Paul Nicholson


3) Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a non-beneficial
interest or in the case of an individual holder if it is a holding of that
person's spouse or children under the age of 18 or in respect of a
non-beneficial interest
As in 2 above


4) Name of the registered holder(s) and, if more than one holder, the
number of shares held by each of them (if notified)
As in 2 Above


5) Please state whether notification relates to a person(s) connected
with the Director named in 2 above and identify the connected person(s)



6) Please state the nature of the transaction. For PEP transactions
please indicate whether general/single co PEP and if discretionary/non
discretionary
Regular annual payment of part of Directors Fees in lieu of cash
consideration.


7) Number of shares/amount of
stock acquired
307


8) Percentage of issued class
0.001%


9) Number of shares/amount
of stock disposed
Nil


10) Percentage of issued class
Nil


11) Class of security
10p Ordinary shares


12) Price per share
£17.07


13) Date of transaction
30 November 2001


14) Date company informed
30 November 2001


15) Total holding following this notification
4,741


16) Total percentage holding of issued class following this notification
0.013%


If a director has been granted options by the company please complete the
following boxes

17) Date of grant



18) Period during which or date on which exercisable



19) Total amount paid (if any) for grant of the option



20) Description of shares or debentures involved: class, number



21) Exercise price (if fixed at time of grant) or indication that price
is to be fixed at time of exercise



22) Total number of shares or debentures over which options held
following this notification



23) Any additional information



24) Name of contact and telephone number for queries
Diane Mellett 01763 263233


25) Name and signature of authorised company official responsible for
making this notification

Diane Mellett Company Secretary

Date of Notification 3 December 2001





                                 SCHEDULE 11

         NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS

1) Name of company
Cambridge Antibody Technology


2) Name of director
Uwe Bicker


3) Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a non-beneficial
interest or in the case of an individual holder if it is a holding of that
person's spouse or children under the age of 18 or in respect of a
non-beneficial interest
As in 2 above


4) Name of the registered holder(s) and, if more than one holder, the
number of shares held by each of them (if notified)
As in 2 Above


5) Please state whether notification relates to a person(s) connected
with the Director named in 2 above and identify the connected person(s)



6) Please state the nature of the transaction. For PEP transactions
please indicate whether general/single co PEP and if discretionary/non
discretionary
Regular annual payment of part of Directors Fees in lieu of cash
consideration.


7) Number of shares/amount of
stock acquired
307


8) Percentage of issued class
0.001%


9) Number of shares/amount
of stock disposed
Nil


10) Percentage of issued class
Nil


11) Class of security
10p Ordinary shares


12) Price per share
£17.07


13) Date of transaction
30 November 2001


14) Date company informed
30 November 2001


15) Total holding following this notification
2,458


16) Total percentage holding of issued class following this notification
0.007%


If a director has been granted options by the company please complete the
following boxes

17) Date of grant



18) Period during which or date on which exercisable



19) Total amount paid (if any) for grant of the option



20) Description of shares or debentures involved: class, number



21) Exercise price (if fixed at time of grant) or indication that price
is to be fixed at time of exercise



22) Total number of shares or debentures over which options held
following this notification



23) Any additional information



24) Name of contact and telephone number for queries
Diane Mellett 01763 263233


25) Name and signature of authorised company official responsible for
making this notification

Diane Mellett Company Secretary

Date of Notification 3 December 2001


                                 SCHEDULE 11

         NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS

1) Name of company
Cambridge Antibody Technology


2) Name of director
Aaron Klug


3) Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a non-beneficial
interest or in the case of an individual holder if it is a holding of that
person's spouse or children under the age of 18 or in respect of a
non-beneficial interest
As in 2 above


4) Name of the registered holder(s) and, if more than one holder, the
number of shares held by each of them (if notified)
As in 2 Above


5) Please state whether notification relates to a person(s) connected
with the Director named in 2 above and identify the connected person(s)



6) Please state the nature of the transaction. For PEP transactions
please indicate whether general/single co PEP and if discretionary/non
discretionary
Regular annual payment of part of Directors Fees in lieu of cash
consideration.


7) Number of shares/amount of
stock acquired
307


8) Percentage of issued class
0.001%


9) Number of shares/amount
of stock disposed
Nil


10) Percentage of issued class
Nil


11) Class of security
10p Ordinary shares


12) Price per share
£17.07


13) Date of transaction
30 November 2001


14) Date company informed
30 November 2001


15) Total holding following this notification
28,527


16) Total percentage holding of issued class following this notification
0.080%


If a director has been granted options by the company please complete the
following boxes

17) Date of grant



18) Period during which or date on which exercisable



19) Total amount paid (if any) for grant of the option



20) Description of shares or debentures involved: class, number



21) Exercise price (if fixed at time of grant) or indication that price
is to be fixed at time of exercise



22) Total number of shares or debentures over which options held
following this notification



23) Any additional information



24) Name of contact and telephone number for queries
Diane Mellett 01763 263233


25) Name and signature of authorised company official responsible for
making this notification

Diane Mellett Company Secretary

Date of Notification 3 December 2001

                                 SCHEDULE 11

         NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS

1) Name of company
Cambridge Antibody Technology


2) Name of director
James Foght


3) Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a non-beneficial
interest or in the case of an individual holder if it is a holding of that
person's spouse or children under the age of 18 or in respect of a
non-beneficial interest
As in 2 above


4) Name of the registered holder(s) and, if more than one holder, the
number of shares held by each of them (if notified)
As in 2 Above


5) Please state whether notification relates to a person(s) connected
with the Director named in 2 above and identify the connected person(s)



6) Please state the nature of the transaction. For PEP transactions
please indicate whether general/single co PEP and if discretionary/non
discretionary
Regular annual payment of part of Directors Fees in lieu of cash
consideration.


7) Number of shares/amount of
stock acquired
307


8) Percentage of issued class
0.001%


9) Number of shares/amount
of stock disposed
Nil


10) Percentage of issued class
Nil


11) Class of security
10p Ordinary shares


12) Price per share
£17.07


13) Date of transaction
30 November 2001


14) Date company informed
30 November 2001


15) Total holding following this notification
3,118


16) Total percentage holding of issued class following this notification
0.009%


If a director has been granted options by the company please complete the
following boxes

17) Date of grant



18) Period during which or date on which exercisable



19) Total amount paid (if any) for grant of the option



20) Description of shares or debentures involved: class, number



21) Exercise price (if fixed at time of grant) or indication that price
is to be fixed at time of exercise



22) Total number of shares or debentures over which options held
following this notification



23) Any additional information



24) Name of contact and telephone number for queries
Diane Mellett 01763 263233


25) Name and signature of authorised company official responsible for
making this notification

Diane Mellett Company Secretary

Date of Notification 3 December 2001

                                 SCHEDULE 11

         NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS

1) Name of company
Cambridge Antibody Technology


2) Name of director
John Stocker


3) Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a non-beneficial
interest or in the case of an individual holder if it is a holding of that
person's spouse or children under the age of 18 or in respect of a
non-beneficial interest
As in 2 above


4) Name of the registered holder(s) and, if more than one holder, the
number of shares held by each of them (if notified)
As in 2 Above


5) Please state whether notification relates to a person(s) connected
with the Director named in 2 above and identify the connected person(s)



6) Please state the nature of the transaction. For PEP transactions
please indicate whether general/single co PEP and if discretionary/non
discretionary
Regular annual payment of part of Directors Fees in lieu of cash
consideration.


7) Number of shares/amount of
stock acquired
307


8) Percentage of issued class
0.001%


9) Number of shares/amount
of stock disposed
Nil


10) Percentage of issued class
Nil


11) Class of security
10p Ordinary shares


12) Price per share
£17.07


13) Date of transaction
30 November 2001


14) Date company informed
30 November 2001


15) Total holding following this notification
78,599


16) Total percentage holding of issued class following this notification
0.222%


If a director has been granted options by the company please complete the
following boxes

17) Date of grant



18) Period during which or date on which exercisable



19) Total amount paid (if any) for grant of the option



20) Description of shares or debentures involved: class, number



21) Exercise price (if fixed at time of grant) or indication that price
is to be fixed at time of exercise



22) Total number of shares or debentures over which options held
following this notification



23) Any additional information



24) Name of contact and telephone number for queries
Diane Mellett 01763 263233


25) Name and signature of authorised company official responsible for
making this notification

Diane Mellett Company Secretary

Date of Notification 3 December 2001

                                 SCHEDULE 11

         NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS

1) Name of company
Cambridge Antibody Technology


2) Name of director
Peter Garland


3) Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a non-beneficial
interest or in the case of an individual holder if it is a holding of that
person's spouse or children under the age of 18 or in respect of a
non-beneficial interest
As in 2 above


4) Name of the registered holder(s) and, if more than one holder, the
number of shares held by each of them (if notified)
As in 2 Above


5) Please state whether notification relates to a person(s) connected
with the Director named in 2 above and identify the connected person(s)



6) Please state the nature of the transaction. For PEP transactions
please indicate whether general/single co PEP and if discretionary/non
discretionary
Regular annual payment of part of Directors Fees in lieu of cash
consideration.


7) Number of shares/amount of
stock acquired
659


8) Percentage of issued class
0.020%


9) Number of shares/amount
of stock disposed
Nil


10) Percentage of issued class
Nil


11) Class of security
10p Ordinary shares


12) Price per share
£17.07


13) Date of transaction
30 November 2001


14) Date company informed
30 November 2001


15) Total holding following this notification
41,825


16) Total percentage holding of issued class following this notification
0.0118%


If a director has been granted options by the company please complete the
following boxes

17) Date of grant



18) Period during which or date on which exercisable



19) Total amount paid (if any) for grant of the option



20) Description of shares or debentures involved: class, number



21) Exercise price (if fixed at time of grant) or indication that price
is to be fixed at time of exercise



22) Total number of shares or debentures over which options held
following this notification



23) Any additional information



24) Name of contact and telephone number for queries
Diane Mellett 01763 263233


25) Name and signature of authorised company official responsible for
making this notification

Diane Mellett Company Secretary

Date of Notification 3 December 2001

                                 SCHEDULE 11

         NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS

1) Name of company
Cambridge Antibody Technology


2) Name of director
Kevin Johnson


3) Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a non-beneficial
interest or in the case of an individual holder if it is a holding of that
person's spouse or children under the age of 18 or in respect of a
non-beneficial interest
As in 2 above


4) Name of the registered holder(s) and, if more than one holder, the
number of shares held by each of them (if notified)
As in 2 Above and Computershare Trustees Limited


5) Please state whether notification relates to a person(s) connected
with the Director named in 2 above and identify the connected person(s)



6) Please state the nature of the transaction. For PEP transactions
please indicate whether general/single co PEP and if discretionary/non
discretionary
The issue and allotment of 117 shares pursuant to the Cambridge Antibody
Technology Inland Revenue approved All Employee Share Ownership Plan.


7) Number of shares/amount of
stock acquired
117


8) Percentage of issued class
0.0003%


9) Number of shares/amount
of stock disposed
Nil


10) Percentage of issued class
Nil


11) Class of security
10p Ordinary shares


12) Price per share
£17.07


13) Date of transaction
30 November 2001


14) Date company informed
30 November 2001


15) Total holding following this notification
63,834


16) Total percentage holding of issued class following this notification
0.180%


If a director has been granted options by the company please complete the
following boxes

17) Date of grant



18) Period during which or date on which exercisable



19) Total amount paid (if any) for grant of the option



20) Description of shares or debentures involved: class, number



21) Exercise price (if fixed at time of grant) or indication that price
is to be fixed at time of exercise



22) Total number of shares or debentures over which options held
following this notification



23) Any additional information



24) Name of contact and telephone number for queries
Diane Mellett 01763 263233


25) Name and signature of authorised company official responsible for
making this notification

Diane Mellett Company Secretary

Date of Notification 3 December 2001

                                 SCHEDULE 11

         NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS

1) Name of company
Cambridge Antibody Technology


2) Name of director
David Glover


3) Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a non-beneficial
interest or in the case of an individual holder if it is a holding of that
person's spouse or children under the age of 18 or in respect of a
non-beneficial interest
As in 2 above


4) Name of the registered holder(s) and, if more than one holder, the
number of shares held by each of them (if notified)
As in 2 Above and Computershare Trustees Limited


5) Please state whether notification relates to a person(s) connected
with the Director named in 2 above and identify the connected person(s)



6) Please state the nature of the transaction. For PEP transactions
please indicate whether general/single co PEP and if discretionary/non
discretionary
The issue and allotment of 117 shares pursuant to the Cambridge Antibody
Technology Inland Revenue approved All Employee Share Ownership Plan.


7) Number of shares/amount of
stock acquired
117


8) Percentage of issued class
0.0003%


9) Number of shares/amount
of stock disposed
Nil


10) Percentage of issued class
Nil


11) Class of security
10p Ordinary shares


12) Price per share
£17.07


13) Date of transaction
30 November 2001


14) Date company informed
30 November 2001


15) Total holding following this notification
10,534


16) Total percentage holding of issued class following this notification
0.030%


If a director has been granted options by the company please complete the
following boxes

17) Date of grant



18) Period during which or date on which exercisable



19) Total amount paid (if any) for grant of the option



20) Description of shares or debentures involved: class, number



21) Exercise price (if fixed at time of grant) or indication that price
is to be fixed at time of exercise



22) Total number of shares or debentures over which options held
following this notification



23) Any additional information



24) Name of contact and telephone number for queries
Diane Mellett 01763 263233


25) Name and signature of authorised company official responsible for
making this notification

Diane Mellett Company Secretary

Date of Notification 3 December 2001

                                 SCHEDULE 11

         NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS

1) Name of company
Cambridge Antibody Technology


2) Name of director
John Aston


3) Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a non-beneficial
interest or in the case of an individual holder if it is a holding of that
person's spouse or children under the age of 18 or in respect of a
non-beneficial interest
As in 2 above


4) Name of the registered holder(s) and, if more than one holder, the
number of shares held by each of them (if notified)
As in 2 Above and Computershare Trustees Limited


5) Please state whether notification relates to a person(s) connected
with the Director named in 2 above and identify the connected person(s)



6) Please state the nature of the transaction. For PEP transactions
please indicate whether general/single co PEP and if discretionary/non
discretionary
The issue and allotment of 146 shares pursuant to the Cambridge Antibody
Technology Inland Revenue approved All Employee Share Ownership Plan.


7) Number of shares/amount of
stock acquired
146


8) Percentage of issued class
0.0004%


9) Number of shares/amount
of stock disposed
Nil


10) Percentage of issued class
Nil


11) Class of security
10p Ordinary shares


12) Price per share
£17.07


13) Date of transaction
30 November 2001


14) Date company informed
30 November 2001


15) Total holding following this notification
12,725


16) Total percentage holding of issued class following this notification
0.036%


If a director has been granted options by the company please complete the
following boxes

17) Date of grant



18) Period during which or date on which exercisable



19) Total amount paid (if any) for grant of the option



20) Description of shares or debentures involved: class, number



21) Exercise price (if fixed at time of grant) or indication that price
is to be fixed at time of exercise



22) Total number of shares or debentures over which options held
following this notification



23) Any additional information



24) Name of contact and telephone number for queries
Diane Mellett 01763 263233


25) Name and signature of authorised company official responsible for
making this notification

Diane Mellett Company Secretary

Date of Notification 3 December 2001

                                 SCHEDULE 11

         NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS

1) Name of company
Cambridge Antibody Technology


2) Name of director
David Chiswell


3) Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a non-beneficial
interest or in the case of an individual holder if it is a holding of that
person's spouse or children under the age of 18 or in respect of a
non-beneficial interest
As in 2 above


4) Name of the registered holder(s) and, if more than one holder, the
number of shares held by each of them (if notified)
As in 2 Above and Computershare Trustees Limited


5) Please state whether notification relates to a person(s) connected
with the Director named in 2 above and identify the connected person(s)



6) Please state the nature of the transaction. For PEP transactions
please indicate whether general/single co PEP and if discretionary/non
discretionary
The issue and allotment of 117 shares pursuant to the Cambridge Antibody
Technology Inland Revenue approved All Employee Share Ownership Plan.


7) Number of shares/amount of
stock acquired
117


8) Percentage of issued class
0.0003%


9) Number of shares/amount
of stock disposed
Nil


10) Percentage of issued class
Nil


11) Class of security
10p Ordinary shares


12) Price per share
£17.07


13) Date of transaction
30 November 2001


14) Date company informed
30 November 2001


15) Total holding following this notification
476,334


16) Total percentage holding of issued class following this notification
1.343%


If a director has been granted options by the company please complete the
following boxes

17) Date of grant



18) Period during which or date on which exercisable



19) Total amount paid (if any) for grant of the option



20) Description of shares or debentures involved: class, number



21) Exercise price (if fixed at time of grant) or indication that price
is to be fixed at time of exercise



22) Total number of shares or debentures over which options held
following this notification



23) Any additional information



24) Name of contact and telephone number for queries
Diane Mellett 01763 263233


25) Name and signature of authorised company official responsible for
making this notification

Diane Mellett Company Secretary

Date of Notification 3 December 2001