Director Shareholding

Cambridge Antibody Tech Group PLC
5 December 2001

                                 SCHEDULE 11


         NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS



1) Name of company

Cambridge Antibody Technology



2) Name of director

Kevin Johnson



3) Please state whether notification indicates that it is in respect of

holding of the shareholder named in 2 above or in respect of a non-beneficial
interest or in the case of an individual holder if it is a holding of that
person's spouse or children under the age of 18 or in respect of a
non-beneficial interest

As in 2 above



4) Name of the registered holder(s) and, if more than one holder, the

number of shares held by each of them (if notified)

As in 2 Above



5) Please state whether notification relates to a person(s) connected

with the Director named in 2 above and identify the connected person(s)





6) Please state the nature of the transaction. For PEP transactions

please indicate whether general/single co PEP and if discretionary/non

discretionary:

Grant of options under company CSOP scheme.





7) Number of shares/amount of

stock acquired





8) Percentage of issued class





9) Number of shares/amount

of stock disposed





10) Percentage of issued class





11) Class of security

Ordinary 10p shares



12) Price per share





13) Date of transaction





14) Date company informed





15) Total holding following this notification





16) Total percentage holding of issued class following this notification





If a director has been granted options by the company please complete the
following boxes

17) Date of grant

4 December 2001



18) Period during which or date on which exercisable

4 December 2004 - 3 December 2011



19) Total amount paid (if any) for grant of the option

Nil



20) Description of shares or debentures involved: class, number

Ordinary 10p shares - 13,260 shares



21) Exercise price (if fixed at time of grant) or indication that price

is to be fixed at time of exercise

1704p



22) Total number of shares or debentures over which options held

following this notification

111,603



23) Any additional information





24) Name of contact and telephone number for queries

Diane Mellett 01763 263233



25) Name and signature of authorised Company official responsible for

making this notification

Diane Mellett Company Secretary

Date of Notification 5 December 2001

                                 SCHEDULE 11


         NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS



1) Name of company

Cambridge Antibody Technology



2) Name of director

John Aston



3) Please state whether notification indicates that it is in respect of

holding of the shareholder named in 2 above or in respect of a non-beneficial
interest or in the case of an individual holder if it is a holding of that
person's spouse or children under the age of 18 or in respect of a
non-beneficial interest

As in 2 above



4) Name of the registered holder(s) and, if more than one holder, the

number of shares held by each of them (if notified)

As in 2 Above



5) Please state whether notification relates to a person(s) connected

with the Director named in 2 above and identify the connected person(s)





6) Please state the nature of the transaction. For PEP transactions

please indicate whether general/single co PEP and if discretionary/non

discretionary

Grant of options under Company CSOP scheme.



7) Number of shares/amount of

stock acquired





8) Percentage of issued class





9) Number of shares/amount

of stock disposed





10) Percentage of issued class





11) Class of security





12) Price per share





13) Date of transaction





14) Date company informed





15) Total holding following this notification





16) Total percentage holding of issued class following this notification





If a director has been granted options by the company please complete the
following boxes

17) Date of grant

4 December 2001



18) Period during which or date on which exercisable

4 December 2004 - 3 December 2011



19) Total amount paid (if any) for grant of the option

Nil



20) Description of shares or debentures involved: class, number

Ordinary 10p shares - 13,489 shares



21) Exercise price (if fixed at time of grant) or indication that price

is to be fixed at time of exercise

1704p



22) Total number of shares or debentures over which options held

following this notification

202,472



23) Any additional information





24) Name of contact and telephone number for queries

Diane Mellett 01763 263233



25) Name and signature of authorised company official responsible for

making this notification

Diane Mellett Company Secretary

Date of Notification 5 December 2001

                                 SCHEDULE 11


         NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS



1) Name of company

Cambridge Antibody Technology



2) Name of director

David Glover



3) Please state whether notification indicates that it is in respect of

holding of the shareholder named in 2 above or in respect of a non-beneficial
interest or in the case of an individual holder if it is a holding of that
person's spouse or children under the age of 18 or in respect of a
non-beneficial interest

As in 2 above



4) Name of the registered holder(s) and, if more than one holder, the

number of shares held by each of them (if notified)

As in 2 Above



5) Please state whether notification relates to a person(s) connected

with the Director named in 2 above and identify the connected person(s)





6) Please state the nature of the transaction. For PEP transactions

please indicate whether general/single co PEP and if discretionary/non

discretionary

Grant of options under Company CSOP scheme.



7) Number of shares/amount of

stock acquired





8) Percentage of issued class





9) Number of shares/amount

of stock disposed





10) Percentage of issued class





11) Class of security





12) Price per share





13) Date of transaction





14) Date company informed





15) Total holding following this notification





16) Total percentage holding of issued class following this notification





If a director has been granted options by the company please complete the
following boxes

17) Date of grant

4 December 2001



18) Period during which or date on which exercisable

4 December 2004 - 3 December 2011



19) Total amount paid (if any) for grant of the option

Nil



20) Description of shares or debentures involved: class, number

Ordinary 10p shares - 13,260 shares



21) Exercise price (if fixed at time of grant) or indication that price

is to be fixed at time of exercise

1704p



22) Total number of shares or debentures over which options held

following this notification

113,243



23) Any additional information





24) Name of contact and telephone number for queries

Diane Mellett 01763 263233



25) Name and signature of authorised company official responsible for

making this notification

Diane Mellett Company Secretary

Date of Notification 5 December 2001

                                 SCHEDULE 11


         NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS



1) Name of company

Cambridge Antibody Technology



2) Name of director

David Chiswell



3) Please state whether notification indicates that it is in respect of

holding of the shareholder named in 2 above or in respect of a non-beneficial
interest or in the case of an individual holder if it is a holding of that
person's spouse or children under the age of 18 or in respect of a
non-beneficial interest

As in 2 above



4) Name of the registered holder(s) and, if more than one holder, the

number of shares held by each of them (if notified)

As in 2 Above



5) Please state whether notification relates to a person(s) connected

with the Director named in 2 above and identify the connected person(s)





6) Please state the nature of the transaction. For PEP transactions

please indicate whether general/single co PEP and if discretionary/non

discretionary

Grant of options under Company CSOP scheme.



7) Number of shares/amount of

stock acquired





8) Percentage of issued class





9) Number of shares/amount

of stock disposed





10) Percentage of issued class





11) Class of security





12) Price per share





13) Date of transaction





14) Date company informed





15) Total holding following this notification





16) Total percentage holding of issued class following this notification





If a director has been granted options by the company please complete the
following boxes

17) Date of grant

4 December 2001



18) Period during which or date on which exercisable

4 December 2004 - 3 December 2011



19) Total amount paid (if any) for grant of the option

Nil



20) Description of shares or debentures involved: class, number

Ordinary 10p shares - 259,934



21) Exercise price (if fixed at time of grant) or indication that price

is to be fixed at time of exercise

1704p



22) Total number of shares or debentures over which options held

following this notification

259,934



23) Any additional information





24) Name of contact and telephone number for queries

Diane Mellett 01763 263233



25) Name and signature of authorised company official responsible for

making this notification

Diane Mellett Company Secretary

Date of Notification 5 December 2001