Director Shareholding

Cambridge Antibody Tech Group PLC
10 December 2001

                                 SCHEDULE 11

         NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS

1) Name of company
Cambridge Antibody Technology


2) Name of director
David Chiswell


3) Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a non-beneficial
interest or in the case of an individual holder if it is a holding of that
person's spouse or children under the age of 18 or in respect of a
non-beneficial interest
(i) As in 2 above
(ii) As in 2 above

(iii) As in 2 above

4) Name of the registered holder(s) and, if more than one holder, the
number of shares held by each of them (if notified)
(i) Linda Chiswell (spouse)
(ii) David Chiswell

(iii) Computershare Trustees Limited



5) Please state whether notification relates to a person(s) connected
with the Director named in 2 above and identify the connected person(s)
(i) Spouse
(ii) As in 2 above

(III) As in 2 above

6) Please state the nature of the transaction. For PEP transactions
please indicate whether general/single co PEP and if discretionary/non
discretionary
(i) Sale of 34,484 shares
(ii) The purchase of 66 shares pursuant to the Cambridge Antibody Technology
Inland Revenue approved All Employee Share Ownership Plan

(iii) The grant of 66 'Free' matching shares pursuant to the Cambridge
Antibody Technology Inland Revenue approved All Employee Share Ownership Plan

7) Number of shares/amount of
stock acquired
(i) Nil
(ii) 66 shares

(iii) 66 shares

8) Percentage of issued class
(i) Nil

(ii) 0.0002%

(iii) 0.0002%


9) Number of shares/amount
of stock disposed
(i) 34,484

(ii) Nil

(iii) Nil


10) Percentage of issued class
(i) 0.097%

(ii) Nil

(iii) Nil


11) Class of security
Ordinary 10p shares


12) Price per share
(i) 1702p

(ii) 1692p

(iii) 1692p


13) Date of transaction
7 December 2001


14) Date company informed
10 December 2001


15) Total holding following this notification
441,865


16) Total percentage holding of issued class following this notification
1.244%


If a director has been granted options by the company please complete the
following boxes

17) Date of grant



18) Period during which or date on which exercisable



19) Total amount paid (if any) for grant of the option



20) Description of shares or debentures involved: class, number



21) Exercise price (if fixed at time of grant) or indication that price
is to be fixed at time of exercise



22) Total number of shares or debentures over which options held
following this notification



23) Any additional information



24) Name of contact and telephone number for queries
Diane Mellett 01763 263233


25) Name and signature of authorised company official responsible for
making this notification

Diane Mellett, Company Secretary

Date of Notification 10 December 2001



                                 SCHEDULE 11

         NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS

1) Name of company
Cambridge Antibody Technology


2) Name of director
John Aston


3) Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a non-beneficial
interest or in the case of an individual holder if it is a holding of that
person's spouse or children under the age of 18 or in respect of a
non-beneficial interest
(i) As in 2 above
(ii) As in 2 above

4) Name of the registered holder(s) and, if more than one holder, the
number of shares held by each of them (if notified)
(i) John Aston

(ii) Computershare Trustees Limited


5) Please state whether notification relates to a person(s) connected
with the Director named in 2 above and identify the connected person(s)
As in 2 above


6) Please state the nature of the transaction. For PEP transactions
please indicate whether general/single co PEP and if discretionary/non
discretionary
(i) The purchase of 66 shares pursuant to the Cambridge Antibody Technology
Inland Revenue approved All Employee Share Ownership Plan.
(ii) The grant of 66 'Free' matching shares pursuant to the Cambridge Antibody
Technology Inland Revenue approved All Employee Share Ownership Plan

7) Number of shares/amount of stock acquired
(i) 66 shares

(ii) 66 shares


8) Percentage of issued class
(i) 0.0002%
(ii) 0.0002%

9) Number of shares/amount of stock disposed
Nil


10) Percentage of issued class
Nil


11) Class of security
Ordinary 10p shares


12) Price per share
£16.92


13) Date of transaction
7 December 2001


14) Date company informed
10 December 2001


15) Total holding following this notification
10,666


16) Total percentage holding of issued class following this notification
0.030%


If a director has been granted options by the company please complete the
following boxes

17) Date of grant



18) Period during which or date on which exercisable



19) Total amount paid (if any) for grant of the option



20) Description of shares or debentures involved: class, number



21) Exercise price (if fixed at time of grant) or indication that price
is to be fixed at time of exercise



22) Total number of shares or debentures over which options held
following this notification



23) Any additional information



24) Name of contact and telephone number for queries
Diane Mellett 01763 263233


25) Name and signature of authorised company official responsible for
making this notification
Diane Mellett, Company Secretary


Date of Notification 10 December 2001



                                 SCHEDULE 11

         NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS

1) Name of company
Cambridge Antibody Technology


2) Name of director
David Glover


3) Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a non-beneficial
interest or in the case of an individual holder if it is a holding of that
person's spouse or children under the age of 18 or in respect of a
non-beneficial interest
(i) As in 2 above
(ii) As in 2 above

4) Name of the registered holder(s) and, if more than one holder, the
number of shares held by each of them (if notified)
(i) David Glover

(ii) Computershare Trustees Limited


5) Please state whether notification relates to a person(s) connected
with the Director named in 2 above and identify the connected person(s)
As in 2 above


6) Please state the nature of the transaction. For PEP transactions
please indicate whether general/single co PEP and if discretionary/non
discretionary
(i) The purchase of 66 shares pursuant to the Cambridge Antibody Technology
Inland Revenue approved All Employee Share Ownership Plan
(ii) The grant of 66 'Free' matching shares pursuant to the Cambridge Antibody
Technology Inland Revenue approved All Employee Share Ownership Plan

7) Number of shares/amount of stock acquired
(i) 66 shares

(ii) 66 shares


8) Percentage of issued class
(i) 0.0002%
(ii) 0.0002%

9) Number of shares/amount of stock disposed
Nil


10) Percentage of issued class
Nil


11) Class of security
Ordinary 10p shares


12) Price per share
£16.92


13) Date of transaction
7 December 2001


14) Date company informed
10 December 2001


15) Total holding following this notification
12,857


16) Total percentage holding of issued class following this notification
0.036%


If a director has been granted options by the company please complete the
following boxes

17) Date of grant



18) Period during which or date on which exercisable



19) Total amount paid (if any) for grant of the option



20) Description of shares or debentures involved: class, number



21) Exercise price (if fixed at time of grant) or indication that price
is to be fixed at time of exercise



22) Total number of shares or debentures over which options held
following this notification



23) Any additional information



24) Name of contact and telephone number for queries
Diane Mellett


25) Name and signature of authorised company official responsible for
making this notification
Diane Mellett, Company Secretary


Date of Notification 10 December 2001