Director Shareholding

Cambridge Antibody Tech Group PLC
25 November 2002

                                  SCHEDULE 11

          NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS


1)      Name of company

Cambridge Antibody Technology

2)  Name of director

Kevin Johnson

3)  Please state whether notification indicates that it is in respect of
    holding of the shareholder named in 2 above or in respect of a
non-beneficial interest or in the case of an individual holder if it is a
holding of that person's spouse or children under the age of 18 or in respect of
a non-beneficial interest

As in 2 above

4)  Name of the registered holder(s) and, if more than one holder, the
    number of shares held by each of them (if notified)

Computershare Trustees Limited

5)  Please state whether notification relates to a person(s) connected
    with the Director named in 2 above and identify the connected person(s)

As in 2 above

6)  Please state the nature of the transaction. For PEP transactions
    please indicate whether general/single co PEP and if discretionary/non
    discretionary

Award of free shares under Inland Revenue Approved Share Incentive Plan

7)  Number of shares/amount of
    stock acquired

253

8)  Percentage of issued class

0.0007%

9)  Number of shares/amount
    of stock disposed

0

10) Percentage of issued class

0%

11) Class of security

Ordinary 10 pence shares

12) Price per share

£5.13

13) Date of transaction

22 November 2002

14) Date company informed

22 November 2002

15) Total holding following this notification

64,087

16) Total percentage holding of issued class following this notification

0.18%

If a director has been granted options by the company please complete the
following boxes

17) Date of grant

22 November 2002

18) Period during which or date on which exercisable

Exercisable from 22 November 2005 to 21 November 2012 subject to satisfaction of
performance condition

19) Total amount paid (if any) for grant of the option

Nil

20) Description of shares or debentures involved: class, number

Grant of 7,451 options over ordinary 10 pence shares under Company Share Option
Plan

21) Exercise price (if fixed at time of grant) or indication that price
    is to be fixed at time of exercise

£5.13

22) Total number of shares or debentures over which options held
    following this notification

119,054

23) Any additional information

None

24) Name of contact and telephone number for queries


Justin Hoskins, 01763 263233


25) Name and signature of authorised company official responsible for
    making this notification



Diane Mellett, Company Secretary

    Date of Notification 25 November 2002





                                  SCHEDULE 11

          NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS


1)      Name of company

Cambridge Antibody Technology

2)  Name of director

John Aston

3)  Please state whether notification indicates that it is in respect of
    holding of the shareholder named in 2 above or in respect of a
non-beneficial interest or in the case of an individual holder if it is a
holding of that person's spouse or children under the age of 18 or in respect of
a non-beneficial interest

As in 2 above

4)  Name of the registered holder(s) and, if more than one holder, the
    number of shares held by each of them (if notified)

Computershare Trustees Limited

5)  Please state whether notification relates to a person(s) connected
    with the Director named in 2 above and identify the connected person(s)

As in 2 above

6)  Please state the nature of the transaction. For PEP transactions
    please indicate whether general/single co PEP and if discretionary/non
    discretionary

Award of free shares under Inland Revenue Approved Share Incentive Plan

7)  Number of shares/amount of
    stock acquired

331

8)  Percentage of issued class

0.0009%

9)  Number of shares/amount
    of stock disposed

0

10) Percentage of issued class

0%

11) Class of security

Ordinary 10 Pence

12) Price per share

£5.13

13) Date of transaction

22 November 2002

14) Date company informed

22 November 2002

15) Total holding following this notification

28,188

16) Total percentage holding of issued class following this notification

0.08%

If a director has been granted options by the company please complete the
following boxes

17) Date of grant

22 November 2002

18) Period during which or date on which exercisable

Exercisable from 22 November 2005 to 21 November 2012 subject to satisfaction of
performance condition

19) Total amount paid (if any) for grant of the option

Nil

20) Description of shares or debentures involved: class, number

Grant of 7,579 options over ordinary 10 pence shares under Company Share Option
Plan

21) Exercise price (if fixed at time of grant) or indication that price
    is to be fixed at time of exercise


£5.13

22) Total number of shares or debentures over which options held
    following this notification

196,051

23) Any additional information

None

24) Name of contact and telephone number for queries

Justin Hoskins, 01763 263233

25) Name and signature of authorised company official responsible for
    making this notification


Diane Mellett, Company Secretary


    Date of Notification 25 November 2002





                                  SCHEDULE 11

          NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS


1)      Name of company

Cambridge Antibody Technology

2)  Name of director

David Glover

3)  Please state whether notification indicates that it is in respect of
    holding of the shareholder named in 2 above or in respect of a
non-beneficial interest or in the case of an individual holder if it is a
holding of that person's spouse or children under the age of 18 or in respect of
a non-beneficial interest

As in 2 above

4)  Name of the registered holder(s) and, if more than one holder, the
    number of shares held by each of them (if notified)

Computershare Trustees Limited

5)  Please state whether notification relates to a person(s) connected
    with the Director named in 2 above and identify the connected person(s)

As in 2 above

6)  Please state the nature of the transaction. For PEP transactions
    please indicate whether general/single co PEP and if discretionary/non
    discretionary

Award of free shares under Inland Revenue Approved Share Incentive Plan

7)  Number of shares/amount of
    stock acquired

253

8)  Percentage of issued class

0.0007%

9)  Number of shares/amount
    of stock disposed

0

10) Percentage of issued class

0%

11) Class of security


Ordinary 10 pence shares


12) Price per share

£5.13

13) Date of transaction

22 November 2002

14) Date company informed

22 November 2002

15) Total holding following this notification

10,919

16) Total percentage holding of issued class following this notification

0.03%

If a director has been granted options by the company please complete the
following boxes

17) Date of grant

22 November 2002

18) Period during which or date on which exercisable

Exercisable from 22 November 2005 to 21 November 2012 subject to the
satisfaction of performance condition

19) Total amount paid (if any) for grant of the option

Nil

20) Description of shares or debentures involved: class, number

Grant of 7,451 options over 10 pence ordinary shares under Company Share Option
Plan

21) Exercise price (if fixed at time of grant) or indication that price
    is to be fixed at time of exercise

£5.13

22) Total number of shares or debentures over which options held
    following this notification

120,694

23) Any additional information

None

24) Name of contact and telephone number for queries

Justin Hoskins, 01763 263233


25) Name and signature of authorised company official responsible for
    making this notification


Diane Mellett, Company Secretary


    Date of Notification 25 November, 2002 November 2002





                                  SCHEDULE 11

          NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS


1)      Name of company

Cambridge Antibody Technology


2)  Name of director


Aaron Klug

3)  Please state whether notification indicates that it is in respect of
    holding of the shareholder named in 2 above or in respect of a
non-beneficial interest or in the case of an individual holder if it is a
holding of that person's spouse or children under the age of 18 or in respect of
a non-beneficial interest


As in 2 above


4)  Name of the registered holder(s) and, if more than one holder, the
    number of shares held by each of them (if notified)

Greenwood Nominees Limited

5)  Please state whether notification relates to a person(s) connected
    with the Director named in 2 above and identify the connected person(s)

As in 2 above

6)  Please state the nature of the transaction. For PEP transactions
    please indicate whether general/single co PEP and if discretionary/non
    discretionary

Regular annual payment of part of directors fee in lieu of cash consideration


7)  Number of shares/amount of
    stock acquired

1,023

8)  Percentage of issued class

0.003%

9)  Number of shares/amount
    of stock disposed

0

10) Percentage of issued class

0%

11) Class of security

Ordinary 10 pence

12) Price per share

£5.13

13) Date of transaction

22 November 2002

14) Date company informed

22 November 2002

15) Total holding following this notification

28,950

16) Total percentage holding of issued class following this notification

0.08%

If a director has been granted options by the company please complete the
following boxes

17) Date of grant



18) Period during which or date on which exercisable



19) Total amount paid (if any) for grant of the option



20) Description of shares or debentures involved: class, number



21) Exercise price (if fixed at time of grant) or indication that price
    is to be fixed at time of exercise



22) Total number of shares or debentures over which options held
    following this notification



23) Any additional information

None

24) Name of contact and telephone number for queries

Justin Hoskins, 01763 263233

25) Name and signature of authorised company official responsible for
    making this notification


Diane Mellett, Company Secretary


    Date of Notification 25 November 2002





                                  SCHEDULE 11

          NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS


1)      Name of company

Cambridge Antibody Technology

2)  Name of director

Peter Garland

3)  Please state whether notification indicates that it is in respect of
    holding of the shareholder named in 2 above or in respect of a
non-beneficial interest or in the case of an individual holder if it is a
holding of that person's spouse or children under the age of 18 or in respect of
a non-beneficial interest

As in 2 above

4)  Name of the registered holder(s) and, if more than one holder, the
    number of shares held by each of them (if notified)

Greenwood Nominees Limited

5)  Please state whether notification relates to a person(s) connected
    with the Director named in 2 above and identify the connected person(s)

As in 2 above

6)  Please state the nature of the transaction. For PEP transactions
    please indicate whether general/single co PEP and if discretionary/non
    discretionary

Regular annual payment of directors fee in lieu of cash consideration

7)      Number of shares/amount of
    stock acquired

2,192

8)  Percentage of issued class

0.006%

9)  Number of shares/amount
    of stock disposed


0

10) Percentage of issued class

0%

11) Class of security

Ordinary 10 pence shares

12) Price per share

£5.13

13) Date of transaction

22 November 2002

14) Date company informed

22 November 2002

15) Total holding following this notification

40,017

16) Total percentage holding of issued class following this notification

0.11%

If a director has been granted options by the company please complete the
following boxes

17) Date of grant



18) Period during which or date on which exercisable



19) Total amount paid (if any) for grant of the option



20) Description of shares or debentures involved: class, number



21) Exercise price (if fixed at time of grant) or indication that price
    is to be fixed at time of exercise



22) Total number of shares or debentures over which options held
    following this notification



23) Any additional information

None

24) Name of contact and telephone number for queries


Justin Hoskins, 01763 263233


25) Name and signature of authorised company official responsible for
    making this notification



Diane Mellett, Company Secretary

    Date of Notification 25 November 2002





                                  SCHEDULE 11

          NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS


1)      Name of company

Cambridge Antibody Technology

2)  Name of director

John Stocker

3)  Please state whether notification indicates that it is in respect of
    holding of the shareholder named in 2 above or in respect of a
non-beneficial interest or in the case of an individual holder if it is a
holding of that person's spouse or children under the age of 18 or in respect of
a non-beneficial interest

As in 2 above

4)  Name of the registered holder(s) and, if more than one holder, the
    number of shares held by each of them (if notified)

Greenwood Nominees Limited

5)  Please state whether notification relates to a person(s) connected
    with the Director named in 2 above and identify the connected person(s)

As in 2 above

6)  Please state the nature of the transaction. For PEP transactions
    please indicate whether general/single co PEP and if discretionary/non
    discretionary

Regular annual payment of part of directors fees in lieu of cash consideration

7)  Number of shares/amount of
    stock acquired

1,023

8)  Percentage of issued class

0.003%

9)  Number of shares/amount
    of stock disposed

0

10) Percentage of issued class

0%

11) Class of security

Ordinary 10 pence

12) Price per share

£5.13

13) Date of transaction

22 November 2002

14) Date company informed

22 November 2002

15) Total holding following this notification

79,622

16) Total percentage holding of issued class following this notification

0.22%

If a director has been granted options by the company please complete the
following boxes

17) Date of grant



18) Period during which or date on which exercisable



19) Total amount paid (if any) for grant of the option



20) Description of shares or debentures involved: class, number



21) Exercise price (if fixed at time of grant) or indication that price
    is to be fixed at time of exercise



22) Total number of shares or debentures over which options held
    following this notification



23) Any additional information

None

24) Name of contact and telephone number for queries


Justin Hoskins, 01763 263233
25) Name and signature of authorised company official responsible for
    making this notification


Diane Mellett, Company Secretary


    Date of Notification 25 November 2002





                                  SCHEDULE 11

          NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS


1)      Name of company

Cambridge Antibody Technology

2)  Name of director

James Foght

3)  Please state whether notification indicates that it is in respect of
    holding of the shareholder named in 2 above or in respect of a
non-beneficial interest or in the case of an individual holder if it is a
holding of that person's spouse or children under the age of 18 or in respect of
a non-beneficial interest

As in 2 above

4)  Name of the registered holder(s) and, if more than one holder, the
    number of shares held by each of them (if notified)

Greenwood Nominees Limited

5)  Please state whether notification relates to a person(s) connected
    with the Director named in 2 above and identify the connected person(s)


As in 2 above


6)  Please state the nature of the transaction. For PEP transactions
    please indicate whether general/single co PEP and if discretionary/non
    discretionary

Regular annual payment of part of directors fee in lieu of cash consideration

7)  Number of shares/amount of
    stock acquired

1,023

8)  Percentage of issued class

0.003%

9)  Number of shares/amount
    of stock disposed

0

10) Percentage of issued class

0%

11) Class of security

Ordinary 10 pence

12) Price per share

£5.13

13) Date of transaction

22 November 2002

14) Date company informed

22 November 2002

15) Total holding following this notification

4,141

16) Total percentage holding of issued class following this notification

0.011%

If a director has been granted options by the company please complete the
following boxes

17) Date of grant



18) Period during which or date on which exercisable



19) Total amount paid (if any) for grant of the option



20) Description of shares or debentures involved: class, number



21) Exercise price (if fixed at time of grant) or indication that price
    is to be fixed at time of exercise



22) Total number of shares or debentures over which options held
    following this notification



23) Any additional information

None

24) Name of contact and telephone number for queries

Justin Hoskins, 01763 263233

25) Name and signature of authorised company official responsible for
    making this notification


Diane Mellett, Company Secretary


    Date of Notification 25 November 2002





                                  SCHEDULE 11

          NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS


1)      Name of company

Cambridge Antibody Technology

2)  Name of director

Paul Nicholson

3)  Please state whether notification indicates that it is in respect of
    holding of the shareholder named in 2 above or in respect of a
non-beneficial interest or in the case of an individual holder if it is a
holding of that person's spouse or children under the age of 18 or in respect of
a non-beneficial interest

As in 2 above

4)  Name of the registered holder(s) and, if more than one holder, the
    number of shares held by each of them (if notified)

As in 2 above

5)  Please state whether notification relates to a person(s) connected
    with the Director named in 2 above and identify the connected person(s)

As in 2 above

6)  Please state the nature of the transaction. For PEP transactions
    please indicate whether general/single co PEP and if discretionary/non
    discretionary

Regular annual payment of part of directors fee in lieu of cash consideration

7)  Number of shares/amount of
    stock acquired

1,023

8)  Percentage of issued class

0.003%

9)  Number of shares/amount
    of stock disposed

0

10) Percentage of issued class

0%

11) Class of security

Ordinary 10 pence

12) Price per share

£5.13

13) Date of transaction

22 November 2002

14) Date company informed

22 November 2002

15) Total holding following this notification

5,764

16) Total percentage holding of issued class following this notification

0.02%

If a director has been granted options by the company please complete the
following boxes

17) Date of grant



18) Period during which or date on which exercisable



19) Total amount paid (if any) for grant of the option



20) Description of shares or debentures involved: class, number



21) Exercise price (if fixed at time of grant) or indication that price
    is to be fixed at time of exercise



22) Total number of shares or debentures over which options held
    following this notification



23) Any additional information

None

24) Name of contact and telephone number for queries


Justin Hoskins, 01763 263233


25) Name and signature of authorised company official responsible for
    making this notification


Diane Mellett, Company Secretary


    Date of Notification 25 November 2002





                                  SCHEDULE 11

          NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS


1)      Name of company

Cambridge Antibody Technology

2)  Name of director

Uwe Bicker

3)  Please state whether notification indicates that it is in respect of
    holding of the shareholder named in 2 above or in respect of a
non-beneficial interest or in the case of an individual holder if it is a
holding of that person's spouse or children under the age of 18 or in respect of
a non-beneficial interest

As in 2 above

4)  Name of the registered holder(s) and, if more than one holder, the
    number of shares held by each of them (if notified)

As in 2 above

5)  Please state whether notification relates to a person(s) connected
    with the Director named in 2 above and identify the connected person(s)

As in 2 above

6)  Please state the nature of the transaction. For PEP transactions
    please indicate whether general/single co PEP and if discretionary/non
    discretionary


Regular annual payment of part of directors fee in lieu of cash consideration

7)  Number of shares/amount of
    stock acquired

1,023

8)  Percentage of issued class

0.003%

9)  Number of shares/amount
    of stock disposed

0

10) Percentage of issued class

0%

11) Class of security

Ordinary 10 pence shares

12) Price per share

£5.13

13) Date of transaction

22 November 2002

14) Date company informed

22 November 2002

15) Total holding following this notification

3,481

16) Total percentage holding of issued class following this notification

0.01%

If a director has been granted options by the company please complete the
following boxes

17) Date of grant



18) Period during which or date on which exercisable



19) Total amount paid (if any) for grant of the option



20) Description of shares or debentures involved: class, number



21) Exercise price (if fixed at time of grant) or indication that price
    is to be fixed at time of exercise



22) Total number of shares or debentures over which options held
    following this notification



23) Any additional information

None

24) Name of contact and telephone number for queries

Justin Hoskins, 01763 269441

25) Name and signature of authorised company official responsible for
    making this notification


Diane Mellett, Company Secretary


    Date of Notification 25 November 2002








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