Director Shareholding-Amendmt

Cambridge Antibody Tech Group PLC
11 December 2000


The issuer has made the following amendment to the Director Shareholding
announcement released 1 December 2000 at 13:24 under RNS No 0981V.

The total holding of Peter Garland in Box 15 should read 50,006 and not 49,500
as previously shown.

All other details remain unchanged.

The full corrected version is shown below.



Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
Kevin Johnson

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:


4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
As in 2

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):


6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:
Exercise and sale of 59,242 options granted under Company Share Option Scheme.

7   Number of shares/amount of stock acquired:
59,242

8   Percentage of issued class:
0.17%

9   Number of shares/amount of stock disposed:
59,242

10  Percentage of issued class:
0.17%

11  Class of security:
10p ordinary shares

12  Price per share:
£41.00

13  Date of transaction:
28 September 2000

14  Date company informed:
28 September 2000

15  Total holding following this notification:
63,627 (with spouse)

16  Total percentage holding of issued class following this notification:
0.18%

If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:


18  Period during which or date on which exercisable:


19  Total amount paid (if any) for grant of the option:


20  Description of shares or debentures involved: class, number:


21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:


22  Total number of shares or debentures over which options held following
this notification:


23  Contact name for queries:
Diane Mellett

24  Contact telephone number:
01763 263233

25  Name of company official responsible for making notification:
Company Secretary




Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
David Glover

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:


4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
As in 2 

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):


6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:
Exercise of 45,000 options and sale of 43,000 options granted under Company
Share Option Scheme.

7   Number of shares/amount of stock acquired:
45,000 

8   Percentage of issued class:
0.13%

9   Number of shares/amount of stock disposed:
43,000

10  Percentage of issued class:
0.12%

11  Class of security:
10p ordinary shares

12  Price per share:
£41.00

13  Date of transaction:
28 September 2000

14  Date company informed:
28 September 2000

15  Total holding following this notification:
9,327

16  Total percentage holding of issued class following this notification:
0.03%

If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:


18  Period during which or date on which exercisable:


19  Total amount paid (if any) for grant of the option:


20  Description of shares or debentures involved: class, number:


21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:


22  Total number of shares or debentures over which options held following
this notification:


23  Contact name for queries:
Diane Mellett

24  Contact telephone number:
01763 263233

25  Name of company official responsible for making notification:
Company Secretary




Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
Peter Garland

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:
As in 2

4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
As in 2

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):


6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:
Sale of shares

7   Number of shares/amount of stock acquired:
Nil

8   Percentage of issued class:


9   Number of shares/amount of stock disposed:
32,500

10  Percentage of issued class:
0.09%

11  Class of security:
10p ordinary shares

12  Price per share:
£41.00

13  Date of transaction:
28 September 2000

14  Date company informed:
28 September 2000

15  Total holding following this notification:
50,006 (with spouse)

16  Total percentage holding of issued class following this notification:
0.14%

If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:


18  Period during which or date on which exercisable:


19  Total amount paid (if any) for grant of the option:


20  Description of shares or debentures involved: class, number:


21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:


22  Total number of shares or debentures over which options held following
this notification:


23  Contact name for queries:
Diane Mellett

24  Contact telephone number:
01763 263233

25  Name of company official responsible for making notification:
Company Secretary




Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
David Chiswell

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:
Spouse

4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
Linda Chiswell

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):
Spouse

6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:
Sale of shares

7   Number of shares/amount of stock acquired:
Nil

8   Percentage of issued class:


9   Number of shares/amount of stock disposed:
150,000

10  Percentage of issued class:
0.43%

11  Class of security:
10p ordinary shares

12  Price per share:
£41.00

13  Date of transaction:
28 September 2000

14  Date company informed:
28 September 2000

15  Total holding following this notification:
476,127

16  Total percentage holding of issued class following this notification:
1.36%

If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:


18  Period during which or date on which exercisable:


19  Total amount paid (if any) for grant of the option:


20  Description of shares or debentures involved: class, number:


21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:


22  Total number of shares or debentures over which options held following
this notification:


23  Contact name for queries:
Diane Mellett

24  Contact telephone number:
01763 263233

25  Name of company official responsible for making notification:
Company Secretary




Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
Sir Aaron Klug

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:
As in 2 and spouse

4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
Sir Aaron Klug (15,649)and Lady Liebe Klug (12,408)

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):
As in 2 and Spouse

6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:
Sale of shares

7   Number of shares/amount of stock acquired:
Nil

8   Percentage of issued class:


9   Number of shares/amount of stock disposed:
10,000 

10  Percentage of issued class:
0.03%

11  Class of security:
Ordinary 10p shares

12  Price per share:
£41.00

13  Date of transaction:
28 September 2000

14  Date company informed:
28 September 2000

15  Total holding following this notification:
28,057

16  Total percentage holding of issued class following this notification:
0.08%

If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:


18  Period during which or date on which exercisable:


19  Total amount paid (if any) for grant of the option:


20  Description of shares or debentures involved: class, number:


21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:


22  Total number of shares or debentures over which options held following
this notification:


23  Contact name for queries:
Diane Mellett

24  Contact telephone number:
01763 263233

25  Name of company official responsible for making notification:
Company Secretary





Additional Information:
Correction of announcement.  This is a correction of the announcement
originally made on September 28, 2000 and amended on December 1 in respect of
the dealings of Peter Garland only.

BOX 15 CHANGED TO 50,006 ( PREVIOUSLY 49,500)

REST OF ANNOUNCEMENT UNCHANGED