Directors' Dealings

Cambridge Antibody Tech Group PLC
3 December 1999


Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
John Aston

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:
as in 2

4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
CAT Group Employees Trustees Limited

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):


6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:
Appropriation of shares to IR approved staff share scheme and a grant of
options

7   Number of shares/amount of stock acquired:
500

8   Percentage of issued class:
0.0020%

9   Number of shares/amount of stock disposed:
n/a

10  Percentage of issued class:
n/a

11  Class of security:
10p ordinary share

12  Price per share:
287p

13  Date of transaction:
3 December 199

14  Date company informed:
3 December 1999

15  Total holding following this notification:
2,127

16  Total percentage holding of issued class following this notification:
0.0084%

If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:
3 December 1999

18  Period during which or date on which exercisable:
3 December 2002- 2 December 2006

19  Total amount paid (if any) for grant of the option:
Nil

20  Description of shares or debentures involved: class, number:
55,019 10p ordinary shares

21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:
287p

22  Total number of shares or debentures over which options held following
this notification:
198,983

23  Contact name for queries:
John Aston

24  Contact telephone number:
01763 263 233

25  Name of company official responsible for making notification:
Diane Mellett




Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
David Chiswell

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:
As in 2

4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
CAT Group Employees Trustee Limited

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):


6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:
Appropriation of shares to IR approved staff share scheme and a grant of
options

7   Number of shares/amount of stock acquired:
500

8   Percentage of issued class:
0.0020%

9   Number of shares/amount of stock disposed:
n/a

10  Percentage of issued class:
n/a

11  Class of security:
10p ordinary shares

12  Price per share:
287p

13  Date of transaction:
3rd December 1999

14  Date company informed:
3 December 1999

15  Total holding following this notification:
626,027

16  Total percentage holding of issued class following this notification:
2.46%

If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:
3 December 1999

18  Period during which or date on which exercisable:
3 December 2002- 2 December 2006

19  Total amount paid (if any) for grant of the option:
Nil

20  Description of shares or debentures involved: class, number:
74,155 10p Ordinary shares

21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:
287p

22  Total number of shares or debentures over which options held following
this notification:
240,721

23  Contact name for queries:
John Aston

24  Contact telephone number:
01763 263 233

25  Name of company official responsible for making notification:
Diane Mellett




Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
David Glover

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:
as in 2

4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
CAT Group Employees Trustee Limited

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):


6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:
Appropriation of shares to IR approved staff share scheme and a grant of
options

7   Number of shares/amount of stock acquired:
500

8   Percentage of issued class:
0.0020%

9   Number of shares/amount of stock disposed:
n/a

10  Percentage of issued class:
n/a

11  Class of security:
10p ordinary shares

12  Price per share:
2.87

13  Date of transaction:
3 December 1999

14  Date company informed:
3 December 1999

15  Total holding following this notification:
7,327

16  Total percentage holding of issued class following this notification:
0.029%

If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:
3 December 1999

18  Period during which or date on which exercisable:
3  December 2002- 2 December 2006

19  Total amount paid (if any) for grant of the option:
Nil

20  Description of shares or debentures involved: class, number:
55,019 10p ordinary shares

21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:
287p

22  Total number of shares or debentures over which options held following
this notification:
174,983

23  Contact name for queries:
John Aston

24  Contact telephone number:
01763 263233

25  Name of company official responsible for making notification:
Diane Mellett




Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
Kevin Johnson

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:
As in 2

4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
CAT group Employees Trustees Limited

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):


6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:
Appropriation of shares to IR approved staff share scheme and a grant of
options

7   Number of shares/amount of stock acquired:
500

8   Percentage of issued class:
0.0020%

9   Number of shares/amount of stock disposed:
n/a

10  Percentage of issued class:
n/a

11  Class of security:
10p ordinary shares

12  Price per share:
287p

13  Date of transaction:
10p ordinary shares

14  Date company informed:
10p ordinary shares

15  Total holding following this notification:
63,627

16  Total percentage holding of issued class following this notification:
0.25%

If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:
3 December 1999

18  Period during which or date on which exercisable:
3 December 2002-2 December 2006

19  Total amount paid (if any) for grant of the option:
Nil

20  Description of shares or debentures involved: class, number:
118,324 10p ordinary shares

21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:
287p

22  Total number of shares or debentures over which options held following
this notification:
123,833

23  Contact name for queries:
John Aston

24  Contact telephone number:
01763 263233

25  Name of company official responsible for making notification:
Diane Mellett




Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
James Foght

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:
Non Beneficial Interest in Grant of shares in lieu of non exec renumeration to
Prudential Vector Healthcare Group

4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
Prudential Vector Healthcare Group

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):


6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:
Prudential Vector Healthcare Group

7   Number of shares/amount of stock acquired:
1,742

8   Percentage of issued class:
0.0069%

9   Number of shares/amount of stock disposed:
n/a

10  Percentage of issued class:
n/a

11  Class of security:
10p ordinary shares

12  Price per share:
287p

13  Date of transaction:
3 December 1999

14  Date company informed:
3 December 1999

15  Total holding following this notification:
2,742

16  Total percentage holding of issued class following this notification:
0.011%

If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:


18  Period during which or date on which exercisable:


19  Total amount paid (if any) for grant of the option:


20  Description of shares or debentures involved: class, number:


21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:


22  Total number of shares or debentures over which options held following
this notification:


23  Contact name for queries:
John Aston

24  Contact telephone number:
01763 263233

25  Name of company official responsible for making notification:





Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
Sir Aaron Klug

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:
As in 2

4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
as in 2

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):


6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:
Grant in lieu of non executive renumeration

7   Number of shares/amount of stock acquired:
1,742

8   Percentage of issued class:
0.0069%

9   Number of shares/amount of stock disposed:
n/a

10  Percentage of issued class:
n/a

11  Class of security:
10p ordinary shares

12  Price per share:
287p

13  Date of transaction:
3 december 1999

14  Date company informed:
3 december 1999

15  Total holding following this notification:
38,057

16  Total percentage holding of issued class following this notification:
0.15%

If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:


18  Period during which or date on which exercisable:


19  Total amount paid (if any) for grant of the option:


20  Description of shares or debentures involved: class, number:


21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:


22  Total number of shares or debentures over which options held following
this notification:


23  Contact name for queries:
John Aston

24  Contact telephone number:
01763 263233

25  Name of company official responsible for making notification:





Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
Peter Garland

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:
as in 2

4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
as in 2

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):
as in 2

6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:
Grant in lieu of non executive director renumeration

7   Number of shares/amount of stock acquired:
3,484

8   Percentage of issued class:
0.014%

9   Number of shares/amount of stock disposed:
n/a

10  Percentage of issued class:


11  Class of security:
10p ordinary shares

12  Price per share:
287p

13  Date of transaction:
December 3 1999

14  Date company informed:
December 3 1999

15  Total holding following this notification:
81,736

16  Total percentage holding of issued class following this notification:
0.32%

If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:


18  Period during which or date on which exercisable:


19  Total amount paid (if any) for grant of the option:


20  Description of shares or debentures involved: class, number:


21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:


22  Total number of shares or debentures over which options held following
this notification:


23  Contact name for queries:
John Aston

24  Contact telephone number:
01763 263233

25  Name of company official responsible for making notification:





Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
Uwe Bicker

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:
as in 2 

4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
as in 2 

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):


6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:
Grant of shares in lieu of non executive renumeration

7   Number of shares/amount of stock acquired:
1,742

8   Percentage of issued class:
0.0069%

9   Number of shares/amount of stock disposed:
n/a

10  Percentage of issued class:
n/a

11  Class of security:
10p ordinary shares

12  Price per share:
287p

13  Date of transaction:
3 December 1999

14  Date company informed:
3 December 1999

15  Total holding following this notification:
1,742

16  Total percentage holding of issued class following this notification:
0.0069%

If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:


18  Period during which or date on which exercisable:


19  Total amount paid (if any) for grant of the option:


20  Description of shares or debentures involved: class, number:


21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:


22  Total number of shares or debentures over which options held following
this notification:


23  Contact name for queries:
John Aston

24  Contact telephone number:
01763 263233

25  Name of company official responsible for making notification:





Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
Paul Nicholson

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:
as in 2

4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
as in 2

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):


6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:
grant in lieu of non executive renumeration

7   Number of shares/amount of stock acquired:
1,742

8   Percentage of issued class:
0.0069%

9   Number of shares/amount of stock disposed:
n/a

10  Percentage of issued class:
n/a

11  Class of security:
10p ordinary shares

12  Price per share:
287p

13  Date of transaction:
3 December 1999

14  Date company informed:
3 December 1999

15  Total holding following this notification:
3,742

16  Total percentage holding of issued class following this notification:
0.015%

If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:


18  Period during which or date on which exercisable:


19  Total amount paid (if any) for grant of the option:


20  Description of shares or debentures involved: class, number:


21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:


22  Total number of shares or debentures over which options held following
this notification:


23  Contact name for queries:
John Aston

24  Contact telephone number:
01763 263233

25  Name of company official responsible for making notification:





Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
John Stocker

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:
As in 2 above

4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
As in 2 above

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):


6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:


7   Number of shares/amount of stock acquired:
1,742

8   Percentage of issued class:
0.0069%

9   Number of shares/amount of stock disposed:


10  Percentage of issued class:


11  Class of security:
10p ordinary shares

12  Price per share:
287 pence

13  Date of transaction:
3 December 1999

14  Date company informed:
3 December 1999

15  Total holding following this notification:
2,742

16  Total percentage holding of issued class following this notification:
0.011%

If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:


18  Period during which or date on which exercisable:


19  Total amount paid (if any) for grant of the option:


20  Description of shares or debentures involved: class, number:


21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:


22  Total number of shares or debentures over which options held following
this notification:


23  Contact name for queries:
John Aston

24  Contact telephone number:
01763 263233

25  Name of company official responsible for making notification:



Additional Information: