Holding in Co-Replacement

Cambridge Antibody Tech Group PLC
10 October 2000


The issuer has made the following amendment to the 'Holding in Company'
announcement released 9 October 2000 at 14:59 under RNS No 2371S.

In section 7 the number of shares/amount of stock disposed should read 398,742
and not 2,771,637 as previously shown.

In section 8 the percentage of issued class should read 1.14% and not 7.90% as
previously shown.

In section 12 the total holding should read 2,771,637 and not 398,742 as
previously shown.

In section 13 the total percentage holding of issued class following this
notification should read 7.90% and not 1.14% as previously shown.

All other details remain unchanged.

The full corrected version is shown below.


Schedule 10 - Notification of Major Interests in Shares

1   Name of company:
Cambridge Antibody Technology

2   Name of shareholder having a major interest:
Janus Capital Corporation - Amended Notification

3   Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a non-beneficial
interest or in the case of an individual holder if it is a holding of that
person's spouse or children under the age of 18:
Funds held on behalf of clients and funds managed

4   Name of registered holder(s) and, if more than one holder, the number of
shares held by each of them:
Not disclosed

5   Number of shares/amount of stock acquired:
Nil

6   Percentage of issued class:
Nil

7   Number of shares/amount of stock disposed:
398,742

8   Percentage of issued class:
1.14%

9   Class of security:
10p ordinary shares

10  Date of transaction:
Unknown

11  Date company informed:
9 October 2000

12  Total holding following this notification:
2,771,637

13  Total percentage holding of issued class following this notification:
7.90%

14  Contact name for queries:
Diane Mellett

15 Contact telephone number:
01763 263233

16  Name of company official responsible for making notification:
Company Secretary

17  Date of notification:
10 October 2000



Additional Information: