Holding in Company

Cambridge Antibody Tech Group PLC
23 May 2001



Schedule 10 - Notification of Major Interests in Shares

1   Name of company:
Cambridge Antibody Technology

2   Name of shareholder having a major interest:
Searle Belgium SA

3   Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a non-beneficial
interest or in the case of an individual holder if it is a holding of that
person's spouse or children under the age of 18:
As in 2 above

4   Name of registered holder(s) and, if more than one holder, the number of
shares held by each of them:
As in 2 above

5   Number of shares/amount of stock acquired:
Nil

6   Percentage of issued class:
Nil

7   Number of shares/amount of stock disposed:
340,000

8   Percentage of issued class:
0.96%

9   Class of security:
Ordinary 10p shares

10  Date of transaction:
Not disclosed

11  Date company informed:
23 May 2001

12  Total holding following this notification:
1,035,837

13  Total percentage holding of issued class following this notification:
2.93%

14  Contact name for queries:
Diane Mellett

15 Contact telephone number:
01763 263233

16  Name of company official responsible for making notification:
Company Secretary

17  Date of notification:
23 May 2001


Additional Information: