Holding in Company

Cambridge Antibody Tech Group PLC
14 May 2001



         Schedule 10 - Notification of Major Interests in Shares



1   Name of company:
     
    Cambridge Antibody Technology Group PLC

2   Name of shareholder having a major interest:
     
    Fidelity Investments

3   Please state whether notification indicates that it is in
    respect of holding of the shareholder named in 2 above or in
    respect of a non-beneficial interest or in the case of an
    individual holder if it is a holding of that person's spouse or
    children under the age of 18:
     
    As in 2 above

4   Name of registered holder(s) and, if more than one holder, the
    number of shares held by each of them:

    Chase Nominees Ltd (915,601) State Street Nominees Ltd (273,675)
    HSBC (1,283,596) Nortrust Nominees (1,210) State Street Nominees
    Ltd (29,300)Clydesdale Bank (Head Office) Nominees Ltd (33,682)
    Chase Nominees Ltd (155,400) Bankers Trust (112,200) MSS Nominees
    Ltd (15,700) Bank of New York Europe (11,000) BT Globenet Nominees
    Ltd (11,000)Nortrust Nominees Ltd (92,100) Chase Nominees Ltd
    (120,000) RBS Trust Bank (109,400) HSBC (26,610)Northern Trust
    (45,300) BT Globenet Nominees Ltd (22,000)Morgan Stanley (27,300)
    Bankers Trust (8,800) Bank of New York Europe (10,500) Citibank
    (4,400)

5   Number of shares/amount of stock acquired:

    448,961

6   Percentage of issued class:
   
    1.27%

7   Number of shares/amount of stock disposed:
   
    nil

8   Percentage of issued class:

    nil

9   Class of security:

    Ordinary 10p shares

10  Date of transaction:
 
    Not disclosed

11  Date company informed:
  
    11 May 2001

12  Total holding following this notification:

    3,308,774

13  Total percentage holding of issued class following this
    notification:

    9.35%

14  Contact name for queries:

    Diane Mellett

15  Contact telephone number:

    01223 263233

16  Name of company official responsible for making notification:

    Company Secretary

17  Date of notification:

    11 May 2001