Holding(s) in Company

Cambridge Antibody Tech Group PLC
15 November 2002

                                  SCHEDULE 10

                   NOTIFICATION OF MAJOR INTERESTS IN SHARES


1)   Name of company
Cambridge Antibody Technology


2)   Name of shareholder having a major interest
FMR Corp and Fidelity International Ltd


3)   Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a non-beneficial
interest or in the case of an individual holder if it is a
holding of that person's spouse or children under the age of 18
Non Beneficial


4)   Name of the registered holder(s) and, if more than one holder, the
     number of shares held by each of them
Chase Nominees Limited (1,060,242) State Street Nominees Limited (130,570) HSBC
(1,012,375) Chase Manhattan Bank London (619,982) Chase Nominees Ltd (307,299)
Bankers Trust (277,628) MSS Nominees Ltd (36,600) Bank of New York Europe
(37,700) BT Globenet Nominees Ltd (7,000) Nortrust Nominees Ltd (148,000) RBS
Trust Bank (173,837) HSBC (4,310) Northern Trust (110,607) BT Globenet Nominees
Ltd (47,900) Morgan Stanley (51,739) Bankers Trust (14,700) Bank of New York
Europe (14,400) Citibank (6,100) Bank of New York - London (50,500) JP
Morgan (98,600) Chase Manhattan Bank London (38,400) State Street Nominees Ltd
(38,900) Bank of New York Brussels (77,100) State Street Bank & Trust (14,300)


5)   Number of shares/amount of stock acquired
368,017


6)   Percentage of issued class
1.02%


7)   Number of shares/amount of stock disposed
Nil


8)   Percentage of issued class
Nil


9)   Class of security
Ordinary 10p shares


10)  Date of transaction
Not disclosed


11)  Date company informed
14 November 2002


12)  Total holding following this notification
4,378,789



13)  Total percentage holding of issued class following this notification
12.09%


14)  Any additional information
None of the entitles notified act as a group or in concert with respect to the
interests disclosed.


15)  Name of contact and telephone number for queries
Diane Mellett 01763 263233


16)  Name and signature of authorised company official responsible for
     making this notification


Diane Mellett Company Secretary


     Date of notification 15 November 2002





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