Holding(s) in Company

Cambridge Antibody Tech Group PLC
09 September 2004

                                  SCHEDULE 10

                   NOTIFICATION OF MAJOR INTERESTS IN SHARES


1)   Name of company

Cambridge Antibody Technology

2)   Name of shareholder having a major interest
The Goldman Sachs Group Inc


3)   Please state whether notification indicates that it is in respect of
     holding of the shareholder named in 2 above or in respect of a
     non-beneficial interest or in the case of an individual holder if it is a
     holding of that person's spouse or children under the age of 18
Goldman Sachs Securities (Nominees) Limited           non-beneficial
The Depositary Trust Company, New York               non-beneficial
Goldman Sachs Securities (Nominees) Limited           beneficial
Goldman Sachs International (CREST a/c CREPTEMP)      beneficial
Goldman Sachs JBWere Managed Funds Limited            beneficial


4)   Name of the registered holder(s) and, if more than one holder, the
     number of shares held by each of them
Goldman Sachs Securities (Nominees) Limited           876,025
The Depositary Trust Company, New York                55,700
Goldman Sachs Securities (Nominees) Limited             1,400
Goldman Sachs International (CREST a/c CREPTEMP)      190,674
Goldman Sachs JBWere Managed Funds Limited            122,700


5)   Number of shares/amount of stock acquired
not disclosed


6)   Percentage of issued class
3.03%


7)   Number of shares/amount of stock disposed
None


8)   Percentage of issued class
N/A


9)   Class of security
Ordinary 10 pence shares


10)  Date of transaction
Not known


11)  Date company informed
9 September 2004


12)  Total holding following this notification
1,246,499



13)  Total percentage holding of issued class following this notification
3.03%


14)  Any additional information
None


15)  Name of contact and telephone number for queries
Justin Hoskins 01223 898589


16)  Name and signature of authorised company official responsible for
     making this notification

Diane Mellett, Company Secretary

     Date of notification 9 September 2004



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