Holding(s) in Company

Cambridge Antibody Tech Group PLC
01 June 2006

                   NOTIFICATION OF MAJOR INTERESTS IN SHARES



1. Name of company



Cambridge Antibody Technology Group plc



2. Name of shareholder having a major interest



The Goldman Sachs Group Inc.



3. Please state whether notification indicates that it is in respect of holding
of the shareholder named in 2 above or in respect of a non-beneficial interest
or in the case of an individual holder if it is a holding of that person's
spouse or children under the age of 18



Goldman Sachs Securities (Nominees) Limited           non beneficial

The Depositary Trust Company, New York                    non beneficial

Goldman Sachs Securities (Nominees) Limited                       beneficial

The Depositary Trust Company, New York               beneficial

Goldman Sachs International (CREST a/c CREPTEMP) beneficial



4. Name of the registered holder(s) and, if more than one holder, the number of
shares held by each of them



Goldman Sachs Securities (Nominees) Limited           428,435

The Depositary Trust Company, New York                446,065

Goldman Sachs Securities (Nominees) Limited             1,400

The Depositary Trust Company, New York                    200

Goldman Sachs International (CREST a/c CREPTEMP)     908,983



5. Number of shares / amount of stock acquired



not disclosed



6. Percentage of issued class



not known



7. Number of shares / amount of stock disposed



not known



8. Percentage of issued class



not known



9. Class of security



Ordinary 10 pence shares



10. Date of transaction



not disclosed



11. Date company informed



31May 2006



12. Total holding following this notification



1,785,083



13. Total percentage holding of issued class following this notification



3.355%



14. Any additional information



None



15. Name of contact and telephone number for queries



Justin Hoskins 01223 898589



16. Name and signature of authorised company official responsible for making
this notification



Justin Hoskins, Company Secretary



Date of notification



1 June 2006



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