Holding in Company

CLS Holdings PLC
5 September 2000

Letter to: CLS Holdings PLC
Date:  1 September 2000

Re:  S.198 Companies Act 1985:  as amended by The Disclosure of Interest in
Shares (Amendment) Regulations 1993

I refer to my letter informing you that Phillips & Drew Life Limited, a
subsidiary of UBS Asset Management Holding (No. 2) Limited, (which is also
treated as having an interest in the above shares) had a notifiable interest in
the Company. Phillips & Drew Life Limited and UBS Asset Management Holding (No.
2) Limited wish to inform you that they no longer have a notifiable interest in
the ord 25p share capital of the Company.

Letter from:  Phillips & Drew