Holding in Company

CLS Holdings PLC
6 November 2000

Letter to Company Announcements Office, dated 6 November 2000.

S198 Companies Act 1985

In accordance with paragraph 9.35 of the Listing Rules we now enclose copy
notification received by us from Fidelity Investments dated 3 November 2000.

Letter from CLS Holdings plc.

NOTIFICATIONS UNDER SECTIONS 198 TO 202 -- UK COMPANIES ACT

1. Company in which shares are held:    CLS Holdings Plc

2. Notifiable Interest:                 Ordinary Shares

    
           Fidelity International Limited (FIL)
           P.O. BOX HM 670
           Hamilton HMCX, Bermuda

           Parent holding company for various direct and indirect subsidiaries,
           including Fidelity Investment Services Ltd (FISL), investment 
           managers for various non-US investment companies and institutional 
           clients. (See Schedule A for listing of Registered Shareholders and 
           their holdings).

3.     The notifiable interests also comprise the notifiable interest of

           Mr Edward C Johnson 3d
           82 Devonshire Street
           Boston, MA 02109

           A principal shareholder of Fidelity International Limited.

4.     The notifiable interests include interest held on behalf of authorized
       unit trust schemes in the U.K. notwithstanding the exemption from 
       reporting pursuant to Section 209 (1)(e) of the Companies Act 1985.

5.     These notifications of disclosable interests constitute separate
       notifications of interest in the shares and are combined solely for 
       the purposes of clarity. Nothing herein should be taken to indicate 
       that Fidelity International Limited and its direct and indirect          
      subsidiaries or Mr Edward C Johnson 3d act as a group or in concert in    
     respect of the disclosed interests, or that they are required to submit    
    these notifications on a joint basis.

6.     The disclosable interests arise under section 208(4) (b) of the Act,
       namely where a person, not being the registered holder, is entitled
       to exercise a right conferred by the holding of the shares or to 
       control the exercise of such rights, or under section 203 of the Act
       respectively.

SCHEDULE A

SECURITY: CLS Holdings Plc                                  Amendment No 6


                      SHARES HELD   MANAGEMENT   NOMINEE/REGISTERED
(Ordinary Shares)                      COMPANY     NAME
                       3,829,910     FISL        Clydesdale Bank (Head Office)
                                                 Nominees Limited
                         291,574     FIL         Clydesdale Bank (Head Office)
                                                 Nominees Limited
                       2,570,070     FIL         HSBC, London


TOTAL ORDINARY SHARES: 6,691,554

CURRENT OWNERSHIP PERCENTAGE:   6.00%

SHARES IN ISSUE:      111,596,169

CHANGE IN HOLDINGS SINCE
 LAST FILING:           +699,999 ordinary shares