First Maternity Unit Sales

Deltex Medical Group PLC 15 January 2007 Deltex Medical Group plc First sales of SupraQTM and CardioQTM monitors into maternity units 15 January 2007 Deltex Medical Group plc ('Deltex Medical' or the 'Company'), the UK's leading haemodynamic monitoring company, today announces the first sales of its SupraQ and CardioQ monitors into maternity units. The monitors were acquired by five hospitals in London and the South-East of England. They are to be used to develop protocols for their usage on mothers and their babies before, during and after birth. Following an evaluation phase, a series of randomised controlled clinical trials will be undertaken using the devices. The project is being coordinated by the team at the Royal Free Hospital in London which has successfully used the SupraQ as a research tool in a number of important trials in an obstetric setting over the last four years. The maternity applications for which the CardioQ and SupraQ monitors are being evaluated include: • caesarean sections; there are about 120,000 caesareans each year in the NHS in England and Wales and nearly one in six of these involve complications. The doctors plan to test the role of the SupraQ as a routine monitor for all these patients and determine which patients should have a CardioQ oesophageal probe placed and at what stage. • post-operative monitoring of mothers in critical care; a small but significant proportion of mothers end up in critical care after giving birth having suffered heavy blood loss and are likely to benefit from minimally or non-invasive monitoring of their circulating blood volume. • neo-natal intensive care monitoring; the CardioQ's KDP probes are currently labelled for use on babies of 3kg or over and this project will determine the clinical need to develop the probes for use on smaller (premature) babies. • monitoring of mothers in labour; assessment of the SupraQ for both higher risk patients (pre-eclampsia etc) and as a basic standard of care (for example as an earlier indicator of risk to the baby than provided by foetal heart rate monitoring). Deltex Medical's chief executive, Andy Hill, commented: 'These contracts represent the first use of our monitoring technology in the obstetrics market and our largest commercial sales to date of the SupraQ monitor. The SupraQ is entirely non-invasive, ideal for use on awake patients and allows doctors to make early interventions. We expect the SupraQ to significantly expand the routine clinical applications of flow-based haemodynamic monitoring. Concluding these sales in the year just ended was an important development in its own right. The related evaluation and research projects are a major development as they have the potential to significantly expand over time the existing market for the CardioQ and to establish a clearly defined market for the entirely non-invasive SupraQ. Our approach to this new market is designed to move as quickly as possible from proof of concept to establishing our technology as a standard of care for a large population of patients.' For further information, please contact:- Deltex Medical Group plc 01243 774 837 Nigel Keen, Chairman nk@deltexmedical.com Andy Hill, Chief Executive ah@deltexmedical.com Ewan Phillips, Finance Director ep@deltexmedical.com Gavin Anderson & Company 0207 554 1400 Deborah Walter dwalter@gavinanderson.co.uk Robert Speed rspeed@gavinanderson.co.uk Charles Stanley Securities 020 7149 6457 Philip Davies philip.davies@csysecurities.com Notes for Editors Deltex Medical manufactures and markets the CardioQ monitor, which uses disposable ultra-sound probes inserted into the oesophagus to determine the amount of blood being pumped around the body - 'circulating blood volume'. Reduced circulating blood volume is known as hypovolaemia, which leads to insufficient oxygen being delivered to the organs. This causes medical complications including peripheral and major organ failure which can lead to death. Hypovolaemia, which is akin to severe dehydration, affects virtually every patient having surgery because of the combined effects of pre-operative starvation, the impact of the anaesthetic agents and trauma from the surgery itself. Using fluids and drugs, guided by the CardioQ, to optimise the amount of circulating blood significantly reduces post-operative complications allowing patients to make a faster, more complete recovery and return home earlier. The CardioQ incorporates the Company's proprietary software and a small diameter, easy-to-use, minimally invasive, disposable oesophageal probe that is used for transmitting and receiving an ultra-sound signal. By using this technology, the CardioQ provides clinicians with the ability to haemodynamically optimise critically ill patients and those undergoing routine moderate to major surgery through the controlled administration of fluid and drugs. Haemodynamic optimisation has been scientifically proven to improve the speed and quality of patient recovery and reduce hospital stay. There are already over 1,250 CardioQs currently in use in hospitals worldwide and distribution arrangements are in place in over 30 countries. In addition, there are currently more than 90 clinical publications on the use of the CardioQ which have repeatedly:- • Validated the results of the Monitor against known standards for measuring cardiac output, demonstrating that the technology works • Proved that the CardioQ works in a wide range of surgical procedures • Demonstrated that the Company's technology provides significant health and economic benefits by helping to reduce post-operative complications and length of hospital stays by an average of 30 to 40 per cent for a wide range of patients. The SupraQ is an entirely non-invasive device which uses an ultrasound probe held at the base of the patient's neck to track the flow of blood in the aorta; it presents the same data as the CardioQ in a similar format and is used for taking snapshots or monitoring over short periods. This information is provided by RNS The company news service from the London Stock Exchange
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