Research Update

Deltex Medical Group PLC 06 July 2005 Deltex Medical Group plc CardioQTM delivers excellent results in colorectal surgery patients 6 July 2005: Deltex Medical Group plc ('Deltex Medical' and the 'Company'), today announces further details of the results of a double-blinded prospective randomised controlled clinical trial using its CardioQTM haemodynamic monitoring system on colorectal patients during their operations. The trial was undertaken by surgeons and anaesthetists at the Freeman Hospital in Newcastle-upon-Tyne. In the study, the control group were given fluids intra-operatively at the anaesthetist's discretion whereas the treatment group were given fluids based on an algorithm guided by the CardioQTM. Additional results to those previously announced were presented in Dublin today at the Tripartite Colorectal Meeting (a clinical meeting for colorectal surgeons from the UK, USA and Australia). The study showed that patients treated with the CardioQTM were able to tolerate a full diet after two rather than four days and were independently assessed as fit for discharge from hospital after six rather than nine days. Previously announced results showed that the CardioQTM patients were actually discharged from hospital after seven days and that they suffered considerably fewer post-operative complications. Deltex Medical's Chief Executive, Andy Hill commented: 'The Association of Coloproctology of Great Britain & Ireland produced a report in June 2004 following the results of its audit of bowel cancer treatments in 93 NHS hospitals. The average length of hospital stay was over twelve days, with only six hospitals achieving lengths of stay of under ten days and not one of them doing as well as the CardioQTM patients at the Freeman.' The same report identified average mortality within thirty days of bowel cancer surgery of 6%. None of the 54 CardioQTM patients at the Freeman died; likewise, none of the 64 CardioQTM patients from a similar 2004 study at Worthing hospital died.' For further information, please contact:- Deltex Medical Group plc 01243 774 837 Nigel Keen, Chairman Andy Hill, Chief Executive Ewan Phillips, Finance Director Financial Dynamics 0207 831 3113 David Yates Lucy Briggs Notes for Editors Deltex Medical manufactures and markets the CardioQTM monitor, which uses disposable ultra-sound probes inserted into the oesophagus to determine the amount of blood being pumped around the body - 'circulating blood volume'. Reduced circulating blood volume is known as hypovolaemia, which leads to insufficient oxygen being delivered to the organs. This causes medical complications including peripheral and major organ failure which can lead to death. Hypovolaemia, which is akin to severe dehydration, affects virtually every patient having surgery because of the combined effects of pre-operative starvation, the impact of the anaesthetic agents and trauma from the surgery itself. Using fluids and drugs, guided by the CardioQTM, to optimise the amount of circulating blood significantly reduces post-operative complications allowing patients to make a faster, more complete recovery and return home earlier. The CardioQTM incorporates the Company's proprietary software and a small diameter, easy-to-use, minimally invasive, disposable oesophageal probe that is used for transmitting and receiving an ultra-sound signal. By using this technology, the CardioQTM provides clinicians with the ability to haemodynamically optimise critically ill patients and those undergoing routine moderate to major surgery through the controlled administration of fluid and drugs. Haemodynamic optimisation has been scientifically proven to improve the speed and quality of patient recovery and reduce hospital stay. There are already over 1,250 CardioQTMs currently in use in hospitals worldwide and distribution arrangements are in place in over 30 countries. In addition, there are currently more than 90 clinical publications on the use of the CardioQ TM which have repeatedly:- • validated the results of the Monitor against known standards for measuring cardiac output, demonstrating that the technology works • proved that the CardioQTM works in a wide range of surgical procedures • demonstrated that the Company's technology provides significant health and economic benefits by helping to reduce post-operative complications and length of hospital stays by an average of 30 to 40 per cent for a wide range of patients. This information is provided by RNS The company news service from the London Stock Exchange W
UK 100

Latest directors dealings