Statement re Investment

Eurovestech PLC 5 March 2002 For Immediate Release 5th March, 2002 EUROVESTECH PLC ('Eurovestech') Statement re Investment D-Pharm achieves first milestone payment from Shire Pharmaceuticals, pursuant to Phase II clinical trial for is anti-epileptic agent SPD 421 Eurovestech is pleased to report that one of its investee companies, D-Pharm Ltd ('D-Pharm'), has achieved its first milestone payment pursuant to the Phase II clinical trial progress of SPD 421 as add-on therapy in the treatment of complex partial seizures. SPD 421 is a drug widely used for the treatment of epilepsy, bipolar disorder and migraine prophylaxis. D-Pharm already has R&D collaborations with Nycomed Amersham Imaging and with Eli Lilly & Company. The milestone payment follows a worldwide development and commercialisation agreement between D-Pharm and Shire Pharmaceuticals Group plc made in March 2000 and follows an initial $2 million payment received at that time. Upon the achievement of milestones specified in the agreement, D-Pharm shall receive additional payments that may amount to approximately $50 million. D-Pharm is also entitled to royalty payments derived from future sales of the product. The worldwide market for anti-epileptics in 1999 was valued at over $3.0 billion and is projected to grow to $4.5 billion by 2005. Yet, the market is still largely under-served, with about 20-25% of epilepsy patients still resistant to current anti-epileptic drug treatments. SPD 421 was developed to safely serve the needs of this patient population. Moreover, by reducing doses and side effects it may be possible to expand the use of this important therapeutic agent in additional indications. Dr. Alex Kozak, D-Pharm's President and CEO, said ' The use of SPD 421 in patients is a tremendously exciting event for D-Pharm. We are looking forward to seeing our efforts finally benefit patients.' Commenting on the investment in D-Pharm, Richard Bernstein, Chief Executive of Eurovestech said: ' The milestone payment to D-Pharm represents a significant achievement in the progress towards substantial revenues.' Enquiries: Eurovestech plc Richard Bernstein - Chief Executive Tel 00 44 207 491 0770 richard.bernstein@eurovestech.com This information is provided by RNS The company news service from the London Stock Exchange
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