Senior Management Appointment

EpiStem Holdings plc 05 March 2008 Epistem strengthens management team with the appointment of Lydia Meyer-Turkson as Director of Biomarker Division. Epistem is pleased to announce the appointment of Lydia Meyer-Turkson as Director of its emerging Biomarker Division. Lydia will lead the continued expansion of the Division managing strategic collaborations with Pharmaceutical and Biotechnology companies using Epistem's plucked hair biomarker technology. Lydia brings more than 14 years Business Development experience of Contract Research in drug development. Prior to joining Epistem, Lydia had been VP Business Development at Evotec, where she identified, structured, negotiated and closed drug discovery collaborations in Europe key to the company's business strategies. Lydia has previously held senior commercial roles with US contract research companies including Quintiles and Covance. She holds a BSc and MPhil in Chemistry from University College Cardiff and an MBA from Manchester Business School. On the commencement of her employment with Epistem, Lydia was awarded share options as detailed below. The share options will vest according to the sales performance of the Biomarker Division over the period to 30th June 2011. The share options have an exercise price of 153 pence, being the closing share price on 4th March 2008. Following this award, Lydia will hold the following numbers of share options: Senior Executive Share option New share options Total share option Share options held as holding prior to granted holding after % of issued capital award award L Meyer-Turkson 0 71,918 71,918 1% For further information, please contact: Matthew Walls, CEO/John Rylands, Financial Director Epistem Holdings Plc Tel: +44 (0)161 606 7258 Thilo Hoffmann/Gareth Price Landsbanki Securities (UK) Limited Tel: +44 (0)207 426 9000 Mike Wort / Anna Dunphy De Facto Communications Limited Tel: +44 (0)207 861 3838 This information is provided by RNS The company news service from the London Stock Exchange

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