Offer Update

Genus PLC
02 November 2005



                             FOR IMMEDIATE RELEASE


NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION IN WHOLE OR IN PART IN OR INTO THE

                              EXCLUDED TERRITORIES



                                   GENUS PLC


  ___________________________________________________________________________




On 31 October 2005 Bridgewell Securities Limited, on behalf of Genus plc, made a
recommended cash offer of 63.2p per Sygen Share for Sygen International plc.



Provided below are details of those holders of Sygen Shares who have given to
Genus irrevocable undertakings to accept the Offer in respect of their entire
interest in Sygen Shares (other than the Sygen Directors for whom full details
of their irrevocable undertakings are disclosed in the Offer document posted to
Sygen Shareholders on 31 October 2005) and also details of those Sygen
Shareholders who have provided to Genus non-binding letters of intent to accept
the Offer in respect of their entire interest in Sygen Shares.



Irrevocable Undertakings


Name                                  No. of ordinary shares   Percentage of the Existing Sygen
                                                                         Share Capital
Framlington Investment Management           13,268,000                        4.5
Limited



These irrevocable undertakings will cease to be binding in the event a third
party announces their intention to make a general offer for all the shares in
Sygen which values Sygen at 5 per cent. or more higher than the Offer.





Letters of Intention


Name                                  No. of ordinary shares   Percentage of the Existing Sygen
                                                                         Share Capital
Phoenix Asset Management Partners           32,623,345                       11.0
Limited
INVESCO Asset Management Ltd                27,819,496                        9.4







Enquiries

Genus                                 Telephone: [phone]
Richard Wood / David Timmins

Bridgewell Securities Limited         Telephone: [phone]
Greg Aldridge / Fred Ward

Panmure Gordon (Broking) Limited      Telephone: [phone]
Edward Farmer / Mark Lander





Certain terms used in this announcement have the same meaning as those used in
the Offer document posted to Sygen Shareholders on 31 October 2005 in relation
to the recommended offer by Bridgewell Securities Limited on behalf of Genus plc
for Sygen International Plc.



This announcement is issued by Bridgewell Securities Limited, which is
authorised and regulated in the United Kingdom by the Financial Services
Authority.  Bridgewell Securities Limited is acting exclusively for Genus and no
one else in connection with the Offer and will not be responsible to anyone
other than Genus for providing the protections afforded to customers of
Bridgewell Securities Limited nor for providing advice in relation to the Offer.



Panmure Gordon (Broking) Limited, which is authorised and regulated in the
United Kingdom by the Financial Services Authority for investment business
activities, is acting exclusively for Genus and no one else and will not be
responsible to anyone other than Genus for providing the protections afforded to
customers of Panmure Gordon nor for providing advice in relation to the Offer.



The release, publication or distribution of this announcement in jurisdictions
other than the United Kingdom may be restricted by law and therefore persons in
such jurisdictions into which this announcement is released, published or
distributed should inform themselves about, and observe, such restrictions. Any
failure to comply with the restrictions may constitute a violation of the
securities laws of any such jurisdiction.



The Offer is not being made, directly or indirectly, in or into, or by use of
the mails of, or by any means or instrumentality (including, without limitation,
facsimile transmission, internet, email, telex or telephone) of interstate or
foreign commerce of, or any facility of a national state or other securities
exchange of, the Excluded Territories and subject to certain exceptions cannot
be accepted by any such use, means instrumentality or facility or from the
Excluded Territories.



Neither the Offer nor the Placing constitutes an offer of securities for sale,
or the solicitation of an offer to buy, securities in the United States and the
Placing Shares to be issued pursuant to the Placing have not been and will not
be registered under the United States Securities Act of 1933, or under the laws
of any state, district or other jurisdiction of the Excluded Territories and no
regulatory clearances in respect of Placing Shares have been or will be, applied
for in any jurisdiction. Accordingly, unless an exemption under the US
Securities Act of 1933 or other relevant securities laws is applicable, the
Placing Shares are not being, and may not be offered, sold, resold, delivered or
distributed, directly or indirectly, in or into any of the Excluded Territories
or to, or for the account or benefit of, any person resident in any of the
Excluded Territories.


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