Offer Update

Genus PLC 02 November 2005 FOR IMMEDIATE RELEASE NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION IN WHOLE OR IN PART IN OR INTO THE EXCLUDED TERRITORIES GENUS PLC ___________________________________________________________________________ On 31 October 2005 Bridgewell Securities Limited, on behalf of Genus plc, made a recommended cash offer of 63.2p per Sygen Share for Sygen International plc. Provided below are details of those holders of Sygen Shares who have given to Genus irrevocable undertakings to accept the Offer in respect of their entire interest in Sygen Shares (other than the Sygen Directors for whom full details of their irrevocable undertakings are disclosed in the Offer document posted to Sygen Shareholders on 31 October 2005) and also details of those Sygen Shareholders who have provided to Genus non-binding letters of intent to accept the Offer in respect of their entire interest in Sygen Shares. Irrevocable Undertakings Name No. of ordinary shares Percentage of the Existing Sygen Share Capital Framlington Investment Management 13,268,000 4.5 Limited These irrevocable undertakings will cease to be binding in the event a third party announces their intention to make a general offer for all the shares in Sygen which values Sygen at 5 per cent. or more higher than the Offer. Letters of Intention Name No. of ordinary shares Percentage of the Existing Sygen Share Capital Phoenix Asset Management Partners 32,623,345 11.0 Limited INVESCO Asset Management Ltd 27,819,496 9.4 Enquiries Genus Telephone: 01256 347 107 Richard Wood / David Timmins Bridgewell Securities Limited Telephone: 020 7003 3000 Greg Aldridge / Fred Ward Panmure Gordon (Broking) Limited Telephone: 020 7459 3600 Edward Farmer / Mark Lander Certain terms used in this announcement have the same meaning as those used in the Offer document posted to Sygen Shareholders on 31 October 2005 in relation to the recommended offer by Bridgewell Securities Limited on behalf of Genus plc for Sygen International Plc. This announcement is issued by Bridgewell Securities Limited, which is authorised and regulated in the United Kingdom by the Financial Services Authority. Bridgewell Securities Limited is acting exclusively for Genus and no one else in connection with the Offer and will not be responsible to anyone other than Genus for providing the protections afforded to customers of Bridgewell Securities Limited nor for providing advice in relation to the Offer. Panmure Gordon (Broking) Limited, which is authorised and regulated in the United Kingdom by the Financial Services Authority for investment business activities, is acting exclusively for Genus and no one else and will not be responsible to anyone other than Genus for providing the protections afforded to customers of Panmure Gordon nor for providing advice in relation to the Offer. The release, publication or distribution of this announcement in jurisdictions other than the United Kingdom may be restricted by law and therefore persons in such jurisdictions into which this announcement is released, published or distributed should inform themselves about, and observe, such restrictions. Any failure to comply with the restrictions may constitute a violation of the securities laws of any such jurisdiction. The Offer is not being made, directly or indirectly, in or into, or by use of the mails of, or by any means or instrumentality (including, without limitation, facsimile transmission, internet, email, telex or telephone) of interstate or foreign commerce of, or any facility of a national state or other securities exchange of, the Excluded Territories and subject to certain exceptions cannot be accepted by any such use, means instrumentality or facility or from the Excluded Territories. Neither the Offer nor the Placing constitutes an offer of securities for sale, or the solicitation of an offer to buy, securities in the United States and the Placing Shares to be issued pursuant to the Placing have not been and will not be registered under the United States Securities Act of 1933, or under the laws of any state, district or other jurisdiction of the Excluded Territories and no regulatory clearances in respect of Placing Shares have been or will be, applied for in any jurisdiction. Accordingly, unless an exemption under the US Securities Act of 1933 or other relevant securities laws is applicable, the Placing Shares are not being, and may not be offered, sold, resold, delivered or distributed, directly or indirectly, in or into any of the Excluded Territories or to, or for the account or benefit of, any person resident in any of the Excluded Territories. This information is provided by RNS The company news service from the London Stock Exchange

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