Offer Update

Genus PLC 02 December 2005 2 December 2005 Recommended Cash Offer by Bridgewell Securities Limited on behalf of Genus plc to acquire the entire issued and to be issued share capital of Sygen International plc Offer unconditional in all respects On 28 October 2005 Genus plc announced a recommended cash offer of 63.2 pence per Sygen Share for the entire issued and to be issued ordinary share capital of Sygen International plc. Further to the announcement made by Genus on 25 November 2005 and following admission of the Enlarged Share Capital to trading on AIM which occurred earlier today, the Board of Genus is pleased to announce that the final condition to the Offer has now been satisfied and that the Offer has become unconditional in all respects. As at 3.00 p.m. on 1 December 2005, Genus either owned or had received valid acceptances of the Offer in respect of a total number of 278,719,020 Sygen Shares, representing approximately 94.39 per cent. of the issued ordinary share capital of Sygen. Compulsory acquisition and cancellation of listing As valid acceptances of the Offer have been received in respect of more than nine-tenths in value of the Sygen Shares to which the Offer relates, Genus intends to apply the provisions of sections 428 to 430F of the Act to acquire compulsorily any outstanding Sygen Shares not acquired or agreed to be acquired by or on behalf of Genus pursuant to the Offer or otherwise. Accordingly Genus will shortly be posting formal notices pursuant to section 429(4) of the Companies Act 1985 to those Sygen Shareholders who have not at that time validly accepted the Offer. Genus will take steps to procure the application by Sygen for the cancellation of Sygen's listing on the Official List and from trading on the London Stock Exchange shortly after Admission. It is anticipated that cancellation of listing and trading will take effect no earlier than 28 December 2005. Acceptance of the Offer Sygen Shareholders who have not yet accepted the Offer are urged to complete and despatch their Forms of Acceptance by post or by hand by Lloyds TSB Registrars, The Causeway, Worthing, West Sussex BN99 6DA or by hand (during normal business hours) only at Lloyds TSB Registrars, Princess House, 1 Suffolk Lane, London EC4R 0AX in accordance with the instructions set out in the Offer Document and in the Form of Acceptance as soon as possible and/or follow the procedure for Electronic Acceptance in accordance with instructions set out in the Offer Document so that settlement occurs as soon as possible. Settlement of the cash consideration due under the Offer in respect of acceptances which have been received before Admission and are valid and complete in all respects will be despatched within 14 days of today's date. Settlement of the consideration in respect of further acceptances, which are valid and complete in all respects, will be despatched within 14 days of receipt. Enquiries: Genus 01256 347100 John Hawkins, Chairman Richard Wood, Chief Executive Officer David Timmins, Finance Director Bridgewell (Financial Adviser and Nominated Adviser to Genus) 0207 003 3000 Greg Aldridge Fred Ward Panmure Gordon (Broker to Genus) 0207 459 3600 Edward Farmer Mark Lander Buchanan Communications (PR Adviser to Genus) 0207 466 5000 Charles Ryland Suzanne Brocks Terms used in this announcement shall have the meaning given to them in the Offer Document. Bridgewell, which is authorised and regulated in the United Kingdom by the Financial Services Authority for investment business activities, is acting as financial adviser to Genus in connection with the Offer and other matters referred to in this announcement and no one else and will not be responsible to anyone other than Genus for providing the protections afforded to clients of Bridgewell nor for providing advice in relation to the Offer, or the contents of this announcement or any arrangement referred to herein. Panmure Gordon, which is authorised and regulated in the United Kingdom by the Financial Services Authority for investment business activities, is acting for Genus and no one else and will not be responsible to anyone other than Genus for providing the protections afforded to customers of Panmure Gordon nor for providing advice in relation to the Offer, or this announcement or any arrangement referred to herein. The release, publication or distribution of this announcement in jurisdictions other than the United Kingdom may be restricted by law and therefore persons in such jurisdictions into which this announcement is released, published or distributed should inform themselves about, and observe, such restrictions. Any failure to comply with the restrictions may constitute a violation of the securities laws of any such jurisdiction. The Offer is not being made, directly or indirectly, in or into, or by use of the mails of, or by any means or instrumentality (including, without limitation, facsimile transmission, internet, email, telex or telephone) of interstate or foreign commerce of, or any facility of a national state or other securities exchange of, the Excluded Territories and subject to certain exceptions cannot be accepted by any such use, means, instrumentality or facility or from the Excluded Territories. Neither the Offer nor the Placing constitutes an offer of securities for sale, or the solicitation of an offer to buy, securities in the United States and the Placing Shares to be issued pursuant to the Placing have not been and will not be registered under the United States Securities Act of 1933, or under the laws of any state, district or other jurisdiction of the Excluded Territories and no regulatory clearances in respect of Placing Shares have been or will be, applied for in any jurisdiction. Accordingly, unless an exemption under the US Securities Act of 1933 or other relevant securities laws is applicable, the Placing Shares are not being, and may not be offered, sold, resold, delivered or distributed, directly or indirectly, in or into any of the Excluded Territories or to, or for the account or benefit of, any person resident in any of the Excluded Territories. This announcement does not constitute an offer to sell or an invitation to purchase any securities or the solicitation of an offer to purchase any securities, pursuant to the Offer or otherwise. The Offer has been made solely by the Offer Document and, in the case of Sygen Shares in certificated form, the Form of Acceptance accompanying the Offer Document, which contain the full terms and conditions of the Offer, including details of how the Offer may be accepted. This information is provided by RNS The company news service from the London Stock Exchange

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