Rule 8.1- (Sygen)

Genus PLC
04 November 2005


                                                                        FORM 8.1

          DEALINGS BY OFFERORS, OFFEREE COMPANIES OR THEIR ASSOCIATES
                  FOR THEMSELVES OR FOR DISCRETIONARY CLIENTS
      (Rules 8.1(a) and (b)(i) of The City Code on Takeovers and Mergers)

Name of purchaser/vendor *                      Genus plc

Company dealt in                                Sygen International plc

Relevant security dealt in                      Ordinary shares of 10 pence
                                                each

Name of offeree / offeror with which            Genus plc
associated

Specify category and nature of associate status Offeror
#

Date of dealing                                 4 November 2005

DEALINGS +

Amount bought         Price per unit (currency must be stated)

22,500,000            62.3 pence

Amount sold           Price per unit (currency must be stated)

N/A                   N/A

Resultant total amount and percentage of the same
relevant security owned or controlled                   29,653,185 (10.04%)

IS A SUPPLEMENTAL FORM 8 (DERIVATIVE)/FORM 8 (OPTION) ATTACHED? NO

Date of disclosure                          4 November 2005

Contact name                                Tom Forcier

Telephone number                            020 7614 8399

* Specify the owner or controller in addition to the person dealing. The naming
of nominees or vehicle companies is insufficient. In the case of disclosure of
dealings by fund managers on behalf of discretionary clients, the clients need
not be named.
# See the definition of 'associate' in the Definitions Section of the Code.
+ If disclosing dealings/holdings in derivatives or options, please attach
Supplemental Form 8 (Derivative) or Supplemental Form 8 (Option), as
appropriate.

For details of the Code's dealing disclosure requirements, see Rule 8 and its
Notes which can be viewed on the Takeover Panel's website at
www.thetakeoverpanel.org.uk.



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