Director/PDMR Shareholding

GlaxoSmithKline PLC
27 March 2007

                   
   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


I give below details of changes in the interests of Directors, Persons
Discharging Managerial Responsibility or Connected Persons in the Ordinary
Shares of GlaxoSmithKline plc.

          The Administrators of the GlaxoSmithKline US Retirement 
          Savings Plan ("the Plan") notified GlaxoSmithKline plc on 
          27 March 2007, that as a result of a movement in the fund 
          on 23 March 2007, the number of Ordinary Share ADRs held 
          by the fund had changed from 16,367,902 to 16,399,539 at 
          an average price of $55.48.

The Plan is a discretionary fund of which all employees or former employees of
GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. Two of the
Company's directors, Dr J P Garnier and Dr M M Slaoui are therefore potentially
interested in the shares held in the fund from time to time in the same way as
other employees or former employees of GlaxoSmithKline plc and its subsidiaries.

This notification relates to a transaction notified in accordance with
Disclosure Rule 3.1.4R(1)(b).


S M Bicknell
Company Secretary

27 March 2007


                      This information is provided by RNS
            The company news service from the London Stock Exchange